50638-50-1 Usage
Description
4-BROMO-N,N-DIMETHYL-M-TOLUIDINE, also known as N,N-Dimethyl 4-bromo-3-methylaniline, is an organic compound with a bromine atom attached to a toluidine molecule. It is characterized by its chemical structure, which includes a methyl group and two dimethyl groups attached to the aromatic ring. 4-BROMO-N,N-DIMETHYL-M-TOLUIDINE is known for its potential applications in various industries due to its unique properties.
Uses
Used in Pharmaceutical Industry:
4-BROMO-N,N-DIMETHYL-M-TOLUIDINE is used as a chemical intermediate for the synthesis of pyridinylpyrazoleacetonitriles and pyridinylpyrazoleacetamides. These compounds serve as ROS receptor tyrosine kinase inhibitors, which play a crucial role in the development of novel therapeutic agents for various diseases, including cancer and other conditions related to the overactivation of ROS receptors.
Used in Chemical Synthesis:
In the field of chemical synthesis, 4-BROMO-N,N-DIMETHYL-M-TOLUIDINE is utilized as a key building block for the creation of more complex molecules with specific applications. Its unique structure allows for further functionalization and modification, making it a valuable component in the synthesis of various organic compounds.
Used in Research and Development:
4-BROMO-N,N-DIMETHYL-M-TOLUIDINE is also employed in research and development laboratories for the study of its chemical properties, reactivity, and potential applications in various fields. Researchers use this compound to explore new reaction pathways, develop innovative synthetic methods, and investigate its potential as a precursor for the development of new drugs and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 50638-50-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,6,3 and 8 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 50638-50:
(7*5)+(6*0)+(5*6)+(4*3)+(3*8)+(2*5)+(1*0)=111
111 % 10 = 1
So 50638-50-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H12BrN/c1-7-6-8(11(2)3)4-5-9(7)10/h4-6H,1-3H3
50638-50-1Relevant articles and documents
Unreactive C-N Bond Activation of Anilines via Photoinduced Aerobic Borylation
Ji, Shuohan,Qin, Shengxiang,Yin, Chunyu,Luo, Lu,Zhang, Hua
supporting information, p. 64 - 68 (2021/12/27)
Unreactive C-N bond activation of anilines was achieved by photoinduced aerobic borylation. A diverse range of tertiary and secondary anilines were converted to aryl boronate esters in moderate to good yields with wide functional group tolerance under simple and ambient photochemical conditions. This transformation achieved the direct and facile C-N bond activation of unreactive anilines, providing a convenient and practical route transforming widely available anilines into useful aryl boronate esters.
Making Dimethylamino a Transformable Directing Group by Nickel-Catalyzed C-N Borylation
Zhang, Hua,Hagihara, Shinya,Itami, Kenichiro
supporting information, p. 16796 - 16800 (2015/11/16)
The dimethylamino (Me2N) group is arguably the most versatile functional group capable of highly efficient and site-selective directed aromatic functionalizations at the ortho-, meta-, and para-positions depending on reaction conditions. While the repertoire of Me2N-directed reactions is growing at a rapid pace, the lack of a general method to transform this group to other functionalities hampers its wider application in organic synthesis. Here we report nickel-catalyzed C-N borylations of aryl- and benzyl-dimethylamines that permit the conversion of a huge library of largely underutilized Me2N-containing organic molecules into various functional molecules by taking advantage of the wealth of existing C-B functionalization methods.
(Hetero)-aryl ketones derivatives with antibacterial properties
-
, (2008/06/13)
Conformationally restricted aryl and heteroaryl ketones derived from monic acid have useful antibacterial properties.
