43163-94-6

Basic information

• Product Name: 3-FLUORO-DL-VALINE
• Synonyms: 2-Amino-3-fluoro-4-methylbutyric acid~H-3-F-DL-Val-OH;2-Amino-3-fluoro-4-methylbutyricacid;H-3-F-DL-Val-OH;3-Fluoro-DL-valine,94%;2-Amino-3-fluoro-3-methylButanoicacid;DL-Valine, 3-fluoro-;2-AMINO-3-FLUORO-3-METHYLBUTYRIC ACID;3-FLUOROVALINE
• CAS NO: 43163-94-6
• Molecular Formula: C₅H₁₀FNO₂
• Molecular Weight: 135.14
• EINECS: -0
• Product Categories: pharmacetical
• Mol File: 43163-94-6.mol
• Article Data: 6

Chemical Properties

• Melting Point: ~210 °C (dec.)
• Boiling Point: 242.1 °C at 760 mmHg
• Flash Point: 100.2 °C
• Appearance: /
• Density: 1.172 g/cm³
• Vapor Pressure: 0.0115mmHg at 25°C
• Refractive Index: 1.44
• Storage Temp.: 2-8°C
• PKA: 1.91±0.12(Predicted)
• BRN: 2350377
• CAS DataBase Reference: 3-FLUORO-DL-VALINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-FLUORO-DL-VALINE(43163-94-6)
• EPA Substance Registry System: 3-FLUORO-DL-VALINE(43163-94-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 22-24/25
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 43163-94-6(Hazardous Substances Data)

Usage

General Description

3-Fluoro-DL-Valine is a chemical compound that is synthetically produced. It is classified as a biochemical or organic compound and falls under the sub-category of fluorinated amino acids and analogs. Given its structure, it plays significant roles in biological studies, particularly biochemistry, pharmacology, and molecular genetics. Its molecular formula is C5H10FNO2. 3-Fluoro-DL-Valine should be handled with care, considering its reactive nature, and standard safety procedures should be followed when dealing with this chemical. It has various applications in scientific research and pharmaceutical development, but it's often used as an intermediate in organic synthesis.

InChI:InChI=1/C5H10FNO2/c1-5(2,6)3(7)4(8)9/h3H,7H2,1-2H3,(H,8,9)/t3-/m1/s1

Upstream product

• 1620450-64-7 C₁₃H₁₆FNO₄ 
• 541-47-9 3-Methylbutenoic acid 
• 171078-05-0 4-Fluoro-4-(1-fluoro-1-methyl-ethyl)-2-phenyl-4H-oxazol-5-one 
• 79205-57-5 amino-2 fluoro-3 methyl-3 butanonitrile 
• 50884-94-1 2-Bromo-3-fluoro-3-methyl-butyric acid 
• 6509-07-5 3,3-dimethyloxirane-2-carbonitrile 
• 26429-35-6 3-fluoro-2-hydroxy-3-methylbutanonitrile 
• 83611-25-0 3-fluoro-2-keto-3-methybutanoic acid 
• 4491-47-8 2-phenyl-4-isopropylidene-5(4H)oxazolone 

Downstream Products

• 171348-52-0 2-((tert-butoxycarbonyl)amino)-3-fluoro-3-methylbutanoic acid 
• 293305-68-7 tert-butyl 2-fluoro-1,2-dimethylpropyl carbamate 
• 1620450-64-7 C₁₃H₁₆FNO₄ 
• 1620450-65-8 C₁₃H₁₆FNO₄ 
• 1620450-66-9 C₁₃H₁₆FNO₄ 
• 757242-20-9 (E)-(S)-4-({2-[(S)-2-(tert-Butoxycarbonyl-methyl-amino)-3-methyl-3-phenyl-butyrylamino]-3-fluoro-3-methyl-butyryl}-methyl-amino)-2,5-dimethyl-hex-2-enoic acid 

Relevant articles and documents

HETEROCYCLE-SUBSTITUED TETRACYCLIC COMPOUNDS AND METHODS OF USE THEREOF FOR TREATMENT OF VIRAL DISEASES

The present invention relates to novel Heterocycle-Substituted Tetracyclic Compounds of Formula (I): (I) and pharmaceutically acceptable salts thereof, wherein A, A', R 2 R 3, R 4 and R are as defined herein. The present i

Addition of molecular fluorine to azlactones: General synthetic method of erythro-β-fluorinated α-amino acids

Reaction of molecular fluorine with unsaturated azlactones derived from appropriate aldehydes (or ketones) and benzoylglycine afforded the difluorinated adducts. The reductive amination reaction of the β-fluorinated α-oxoalkanoic acids obtained from the a

NOUVELLE VOIE DE SYNTHESE D'ACIDES AMINES MONOFLUORES

Ring opening of the glycidonitriles (IIa-e) by HF/pyridine leads to the fluorocyanohydrins (IIIa-e).Treatment of the nitriles (IIIa-e) with ammonia in methanol gives the α-amino-β-fluoro nitriles (IVa-e) which upon acidic hydrolysis afford the β-fluoro-α-