2032-34-0 Usage
Description
3,3-Diethoxypropionitrile, a cyanide derivative, is a propionitrile derivative characterized by its clear yellow to brownish liquid appearance. It is known for its chemical reactivity, particularly in the preparation of various biologically active compounds and through different synthetic pathways.
Uses
1. Pharmaceutical Industry:
3,3-Diethoxypropionitrile is used as a key intermediate in the synthesis of biologically active compounds, specifically p38α mitogen-activated protein kinase inhibitors. These inhibitors play a crucial role in the development of medications targeting various diseases and conditions, including inflammatory and autoimmune disorders.
2. Chemical Synthesis:
In the field of chemical synthesis, 3,3-Diethoxypropionitrile is utilized in the preparation of 2-(2,2-diethoxy-ethyl)-pyridine through a [2+2+2]-cycloaddition reaction. 3,3-Diethoxypropionitrile serves as an important building block for further chemical modifications and the creation of novel molecules with potential applications.
3. Organic Chemistry:
3,3-Diethoxypropionitrile may also be used in the synthesis of cyanomalondialdehyde, a compound that can be further transformed into various organic molecules with different applications in research and industry.
4. Research and Development:
Due to its unique chemical properties and reactivity, 3,3-Diethoxypropionitrile is valuable in research and development settings. Scientists and chemists can explore its potential in creating new compounds and understanding its behavior in various chemical reactions.
Synthesis Reference(s)
Journal of the American Chemical Society, 69, p. 2657, 1947 DOI: 10.1021/ja01203a028
Check Digit Verification of cas no
The CAS Registry Mumber 2032-34-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,0,3 and 2 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2032-34:
(6*2)+(5*0)+(4*3)+(3*2)+(2*3)+(1*4)=40
40 % 10 = 0
So 2032-34-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H13NO2/c1-3-9-7(5-6-8)10-4-2/h7H,3-5H2,1-2H3
2032-34-0Relevant articles and documents
3 - Ethoxy acrylonitrile and 3, 3 - diethyl dimethoxypropionitrile is treated mixture of synthetic method
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Paragraph 0037; 0038-0048, (2019/07/05)
The invention belongs to the field of medicinal chemistry, in particular to medicinal chemistry of the in the field of organic synthesis, more in particular to 3 - ethoxy acrylonitrile and 3, 3 - diethyl dimethoxypropionitrile is treated mixture of synthetic method. The method uses acetonitrile with a ester alcohol under the action of the alkali metal salt, to obtain the intermediate compound II, then this compound II and then under the action of the phase transfer catalyst, with the sulfuric acid b b obtained by the target mixture compound I, namely 3 - ethoxy acrylonitrile and 3, 3 - diethyl dimethoxypropionitrile is treated mixture. The invention disclosed 3 - ethoxy acrylonitrile and 3, 3 - diethyl dimethoxypropionitrile is treated mixture of the synthetic method has low material cost, relatively mild reaction conditions, the operation is simple, the yield and the like, which is suitable for the industrial production, application of the method.
Process for producing an acetal
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, (2008/06/13)
An acetal is produced at a high yield and a high selectivity by contacting an olefin and an alcohol with each other in the presence of (a) a nitrite, (b) a platinum group metal or the salts thereof and (c) a halide at a high reaction rate without requirement of any troublesome operations for the separation, recovery and regeneration of the catalyst.