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CAS No.: | 220957-39-1 |
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Name: | 5-Bromofuro[2,3-b]pyridine |
Article Data: | 4 |
Molecular Structure: | |
Formula: | C7H4BrNO |
Molecular Weight: | 198.019 |
Synonyms: | 5-Bromofuro[2,3-b]pyridine;5-broMofuro[2 |
Density: | 1.710 |
Boiling Point: | 226℃ |
Flash Point: | 91℃ |
Hazard Symbols: | Xn |
Risk Codes: | 22 |
PSA: | 26.03000 |
LogP: | 2.59030 |
5-bromo-3-((trimethylsilyl)ethynyl)pyridin-2-oI
5-bromofuro<2,3-b>pyridine
Conditions | Yield |
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With copper(l) iodide; triethylamine In ethanol at 70℃; for 3h; | 32% |
5-bromo-3-ethynyl-2(1H)-pyridinone
5-bromofuro<2,3-b>pyridine
Conditions | Yield |
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In dimethyl sulfoxide at 120℃; for 0.5h; Irradiation; |
5-nitrofuro<2,3-b>pyridine
5-bromofuro<2,3-b>pyridine
Conditions | Yield |
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Multi-step reaction with 2 steps 1: Al(Hg), water / diethyl ether / 3 h / Ambient temperature 2: 1.) 47 percent aq. HBr, NaNO2, 2.) CuBr, 37 percent aq. HBr / 1.) 0 deg C, 15 min View Scheme |
furo[2,3-b]pyridin-5-ylamine
5-bromofuro<2,3-b>pyridine
Conditions | Yield |
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With hydrogen bromide; copper(I) bromide; sodium nitrite 1.) 0 deg C, 15 min; Yield given; Multistep reaction; |
5-bromofuro<2,3-b>pyridine
Conditions | Yield |
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Stage #1: 5-bromofuro<2,3-b>pyridine With bis(di-tert-butyl(4-dimethylaminophenyl)phosphine)dichloropalladium(II); N-Methyldicyclohexylamine; 1,4-diazabicyclo [2.2.2] octane-1,4-diium-1,4-disulfinate In isopropyl alcohol at 110℃; for 1h; Microwave irradiation; Stage #2: With N-fluorobis(benzenesulfon)imide In isopropyl alcohol at 20℃; for 3h; | 42% |
methyl 3-[[(4-methylcyclohexyl)carbonyl](1-methylethyl)amino]-5-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-2-thiophenecarboxylate
5-bromofuro<2,3-b>pyridine
methyl 5-(4-furo[2,3-b]pyridin-5-ylphenyl)-3-[[(4-methylcyclohexyl)carbonyl](1-methylethyl)amino]-2-thiophenecarboxylate
Conditions | Yield |
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With sodium carbonate; tetrakis(triphenylphosphine) palladium(0) In 1,4-dioxane; water at 100℃; for 0.3h; Irradiation; |