2430-01-5Relevant articles and documents
A new facile synthesis of a thromboxane B2 precursor
Booysen,Holzapfel
, p. 1461 - 1472 (1995)
A short, stereocontrolled synthesis of a key intermediate in the synthesis of thromboxane B2 is described. The approach is based on the use of N,N-diethyl(phenylsulfonyl)acetamide as nucleophile in a palladium-catalysed nucleophilic substitutio
Facile peripheral modification of N-confused porphyrin
Qu, Wenchao,Ding, Tang,Cetin, Anil,Harvey, John D.,Taschner, Michael J.,Ziegler, Christopher J.
, p. 811 - 814 (2006)
An improved methodology for the N-alkylation of the porphyrin isomer N-confused porphyrin is presented. The combination of polar solvent conditions and the use of the base Cs2CO3 affords externally modified products in high yield wit
Quaternary ammonium salt type honokiol/magnolol derivative as well as preparation method and application thereof
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Paragraph 0039; 0050-0051, (2021/06/26)
The invention discloses a series of novel quaternary ammonium salt honokiol/magnolol derivatives as well as a preparation method and application thereof. According to the series of compounds, honokiol/magnolol is taken as a raw material, a series of novel quaternary ammonium salt honokiol/magnolol derivatives are prepared on phenolic hydroxyl groups of honokiol/magnolol through a coupling reaction, and the structural general formula is shown in the specification. The compound disclosed by the invention has very strong antibacterial activity on staphylococcus aureus ATCC 29213 and clinically separated methicillin-resistant staphylococcus aureus (MRSA), most of the derivatives are higher than parent honokiol/magnolol, and the activity of part of the target derivatives is higher than that of a contrast drug levofloxacin. The compound is expected to be used for preparing drugs for resisting staphylococcus aureus and methicillin-resistant staphylococcus aureus.
Design, Synthesis, Antimicrobial Evaluation, and Laccase Catalysis Effect of Novel Benzofuran–Oxadiazole and Benzofuran–Triazole Hybrids
Faiz, Sadia,Zahoor, Ameer Fawad,Ajmal, Muhammad,Kamal, Shagufta,Ahmad, Sajjad,Abdelgawad, Abdelrahman M.,Elnaggar, Mehrez E.
, p. 2839 - 2852 (2019/11/03)
Novel structural hybrids of benzofuran–oxadiazole and benzofuran–triazole have been synthesized and evaluated for their potential against Staphylococcus aureus, Bacillus subtilis, and Escherichia coli. The excellent antibiotic activity was shown by compou