598-21-0 Usage
Description
Bromoacetyl bromide is a water-white liquid with a pungent odor, denser than water, and has the potential to irritate skin, eyes, and mucous membranes. It may be toxic through ingestion, inhalation, and skin absorption. This chemical is primarily used to synthesize other chemicals and has various applications across different industries.
Uses
Used in Chemical Synthesis:
Bromoacetyl bromide is used as an acylating agent for the synthesis of fine chemicals, agrochemicals, dyes, and pharmaceuticals. It plays a crucial role in the production of various compounds due to its reactive nature.
Used in Pharmaceutical Industry:
Bromoacetyl bromide is used as a key intermediate in the preparation of 10-bromoacetyl-10H-phenothiazine, which is an important compound in the pharmaceutical industry.
Used in Biodegradable Materials:
Bromoacetyl bromide is used as a reactant in the preparation of bromoactylated starch, a biodegradable thermoplastic copolymer. This application contributes to the development of environmentally friendly materials.
Used in Dye Industry:
In the dye industry, bromoacetyl bromide is utilized for the synthesis of various dyes, showcasing its versatility in chemical reactions and its importance in creating a wide range of colorants.
Used in Agrochemicals:
Bromoacetyl bromide is employed in the synthesis of agrochemicals, which are essential for the agricultural industry to protect crops and enhance their growth. Its use in this sector highlights its significance in contributing to food security and crop protection.
Air & Water Reactions
Fumes in air. Reacts violently with water to form hydrobromic acid (HBr) (USCG 1991).
Reactivity Profile
Bromoacetyl bromide is incompatible with water, with bases (including amines), with strong oxidizing agents, with alcohols. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291]. Decomposes when heated with evolution of highly toxic and irritating hydrogen bromide and bromophosgene vapors.
Health Hazard
Inhalation causes severe irritation of upper respiratory system. External contact causes severe irritation of eyes and skin. Ingestion causes severe irritation of mouth and stomach.
Check Digit Verification of cas no
The CAS Registry Mumber 598-21-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,9 and 8 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 598-21:
(5*5)+(4*9)+(3*8)+(2*2)+(1*1)=90
90 % 10 = 0
So 598-21-0 is a valid CAS Registry Number.
InChI:InChI=1/C2H2Br2O/c3-1-2(4)5/h1H2
598-21-0Relevant articles and documents
Highly selective synthesis of α-bromoesters using molecular bromine catalyzed by phosphorus
Sun, Zhaoyun,Peng, Xinhua,Dong, Xiongzi,Shi, Wenwen
scheme or table, p. 929 - 930 (2012/07/30)
A series of α-bromoesters have been synthesized by applying Hell-Volhard-Zelinsky reaction catalyzed by phosphorus instead of usual phosphorus tribromide. An excellent regioselectivity to good yields are achieved at comparatively mild reaction conditions of an operational simplicity.
Method of synthesizing optically enriched alpha-halo-esters, and product and composition therefrom
-
, (2008/06/13)
A method of synthesizing highly optically enriched alpha-halo-esters comprises reacting acid halides with a cinchona alkaloid catalyst and a base to form intermediate ketenes. The ketenes are reacted with electrophilic halogenating reagents to produce alpha-halo-esters with high enantiomeric excess. The base can be an inorganic salt. The thus-formed alpha-halo-esters have utility in synthesizing other optically-pure materials.
Inhibitors of sorotonin N-acetyltransferase
-
, (2008/06/13)
This invention is directed to a compound having the formula I. STR1 This invention is directed to a pharmaceutical composition comprising a compound which inhibits serotonin N-acetyltransferase having the formula I and a pharmaceutical acceptable carrier. The present invention relates to novel compounds and analogs which inhibit the serotonin N-acetyltransferase enzyme, and to processes for their preparation.