174848-98-7 Usage
Description
(1S,2R)-2-(azidomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide is a chiral compound featuring a cyclopropane ring with a carboxamide group and an azide functional group. It is characterized by its (1S,2R) stereochemistry and contains diethyl and phenyl substituents. (1S,2R)-2-(azidomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide serves as a potential precursor in organic synthesis and chemical research, with potential applications in pharmaceuticals, agrochemicals, and materials science, making it a compound of interest to scientists and researchers.
Uses
Used in Organic Synthesis:
(1S,2R)-2-(azidomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide is used as a precursor in organic synthesis for the generation of reactive intermediates. Its unique structure and functional groups allow for the creation of a variety of complex molecules and compounds.
Used in Chemical Research:
In the field of chemical research, (1S,2R)-2-(azidomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide is utilized to study the properties and reactions of cyclopropane rings, carboxamides, and azide groups. This helps in understanding the reactivity and potential applications of similar compounds.
Used in Pharmaceutical Industry:
(1S,2R)-2-(azidomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide is used as a potential precursor in the development of pharmaceuticals. Its unique structure and functional groups may contribute to the creation of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In agrochemicals, (1S,2R)-2-(azidomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide may be employed as a starting material for the synthesis of new agrochemicals, such as pesticides or herbicides, due to its reactive intermediates and potential biological activity.
Used in Materials Science:
(1S,2R)-2-(azidomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide is also used in materials science for the development of new materials with specific properties. Its unique structure and functional groups can contribute to the creation of advanced materials for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 174848-98-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,4,8,4 and 8 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 174848-98:
(8*1)+(7*7)+(6*4)+(5*8)+(4*4)+(3*8)+(2*9)+(1*8)=187
187 % 10 = 7
So 174848-98-7 is a valid CAS Registry Number.
174848-98-7Relevant articles and documents
AN IMPROVED PROCESS FOR THE PREPARATION OF 1-ARYL 2-AMINOMETHYL CYCLOPROPANE CARBOXYAMIDE (Z) DERIVATIVES, THEIR ISOMERS AND SALTS
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, (2014/02/15)
The present invention relates to an improved and one-pot process for the preparation of 1-Aryl 2-aminomethyl cyclopropane carboxyamide (z) derivatives, their isomers of formula (I) or its pharmaceutically acceptable salt thereof wherein R1 and R2 are represents independently selected from the group consisting of hydrogen, lower alkyl, lower aryl, and lower-alkylaryl, which aryl or alkylaryl group is optionally substituted by a halogen atom.
Synthesis of (+)- and (-)-milnaciprans and their conformationally restricted analogs
Shuto, Satoshi,Ono, Shizuka,Hase, Yukako,Kamiyama, Noriko,Matsuda, Akira
, p. 641 - 644 (2007/10/02)
Reaction of (R)-epichlorohydrin [(R)-5] and phenylacetonitrile (6) in the presence of NaNH2 in benzene gave a cyclopropane derivative which was isolated as lactone 4 [(1S,2R)-2-oxo-1-phenyl-3-oxabicyclo[3,1,0]hexane] of 96% e.e. in 67% yield, after alkaline hydrolysis of the cyano group. Compound 4 was readily converted to (+)-milnacipran [(+)-1], by which the absolute stereochemistry of (+)-1 was confirmed. (1S,2R)-1-phenyl-2-[(S)-1-aminoethyl]-cyclopropane-N,N-diethylcarboxam ides (2), a conformationally restricted analog of 1, was also synthesized in high enantiomeric purity from 4. Starting from (S)-epichlorohydrin [(S)-5], their corresponding enantiomers, namely (-)-milnacipran [(-)-1] and ent-2, were also synthesized.
