105494-65-3

Basic information

• Product Name: TRI-N-BUTYL(1-PROPENYL)TIN
• Synonyms: 1-PROPENYLTRIBUTYLSTANNANE;1-PROPENYLTRIBUTYLTIN;2-METHYLVINYLTRIBUTYLTIN;TRI-N-BUTYL(1-PROPENYL)TIN;TRIBUTYL-1-PROPENYLTIN;1-Propenyltri-n-butylstannane~1-Propenyltri-n-butyltin~1-(Tri-n-butylstannyl)propene;2-Methylvinyltributyltin (cis/trans mixture);Tributyl-1-propenyltin (Z/E mixture)
• CAS NO: 105494-65-3
• Molecular Formula: C₁₅H₃₂Sn
• Molecular Weight: 331.12
• EINECS: -0
• Product Categories: Stannanes
• Mol File: 105494-65-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 90-92 °C (0.4 mmHg)
• Flash Point: 90-92°C/0.4mm
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 0.00087mmHg at 25°C
• Refractive Index: 1.4820
• Storage Temp.: Refrigerator (+4°C)
• BRN: 3935279
• CAS DataBase Reference: TRI-N-BUTYL(1-PROPENYL)TIN(CAS DataBase Reference)
• NIST Chemistry Reference: TRI-N-BUTYL(1-PROPENYL)TIN(105494-65-3)
• EPA Substance Registry System: TRI-N-BUTYL(1-PROPENYL)TIN(105494-65-3)

Safety Data

• Hazard Codes: N-T
• Statements: 50/53-48/23/25-36/38-25-21
• Safety Statements: 61-60-45-36/37/39-35
• RIDADR: 2788
• HazardClass: 6.1
• PackingGroup: II
• Hazardous Substances Data: 105494-65-3(Hazardous Substances Data)

Usage

Description

TRI-N-BUTYL(1-PROPENYL)TIN is an organotin compound, specifically a tin alkyl, characterized by its clear pale yellow liquid appearance. It is a reagent utilized in various chemical reactions and synthesis processes, particularly in the production of complex organic molecules.

Uses

Used in Pharmaceutical Industry:
TRI-N-BUTYL(1-PROPENYL)TIN is used as a synthetic reagent for the production of Englerin A, a compound with potential therapeutic applications. It plays a crucial role in the synthesis process, enabling the creation of this bioactive molecule that may have significant implications in the development of new drugs and treatments.
Used in Chemical Synthesis:
In the field of organic chemistry, TRI-N-BUTYL(1-PROPENYL)TIN serves as a versatile reagent for various chemical reactions. Its unique properties allow it to facilitate the formation of new bonds and functional groups, contributing to the synthesis of a wide range of organic compounds with diverse applications in different industries.

InChI:InChI=1/3C4H9.C3H5.Sn/c3*1-3-4-2;1-3-2;/h3*1,3-4H2,2H3;1,3H,2H3;/rC15H32Sn/c1-5-9-13-16(12-8-4,14-10-6-2)15-11-7-3/h8,12H,5-7,9-11,13-15H2,1-4H3

Upstream product

• 590-14-7 1-bromo-1-propene 
• 1461-22-9 tributyltin chloride 
• 4226-01-1 tri-n-butyltin lithium 
• 74-86-2 acetylene 
• 917-54-4 methyllithium 
• 74-88-4 methyl iodide 
• 27262-82-4 tributylstannylmagnesium chloride 
• 123-38-6 propionaldehyde 
• 75-36-5 acetyl chloride 
• 937-63-3 p-Tolyl chlorothionoformate 
• 116064-59-6 1-tributylstannyl-propan-1-ol 

Downstream Products

• 766-90-5 cis-1-phenyl-1-propylene 
• 120635-31-6 (7R,8R)-7-phenylacetamido-3-[(Z)-propen-1-yl]-3-cephem-4-carboxylic acid p-methoxybenzyl ester 
• 125151-68-0 (6R,7S)-8-Oxo-7-(2-phenoxy-acetylamino)-3-((Z)-propenyl)-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 24647-44-7 diphenylmethyl (6R,7S)-7-(phenoxyacetamido)-3-methylceph-2-em-4-carboxylate 
• 10209-10-6 diphenylmethyl (6R,7R)-3-methyl-7β-phenoxyacetamidoceph-3-em-4-carboxylate 
• 130516-13-1 diphenylmethyl (6R,7S)-7-(phenoxyacetamido)-3-<(Z)-1-propenyl>ceph-3-em-4-carboxylate 
• 31552-04-2 (Z)-1-phenyl-3-penten-1-yne 
• 683276-31-5 (3aS,6aS)-2,2-dimethyl-5-prop-(Z)-enyl-3a,6a-dihydro-cyclopenta[1,3]dioxol-4-one 
• 683276-46-2 (3aR,6aR)-2,2-dimethyl-5-prop-(Z)-enyl-3a,6a-dihydro-cyclopenta[1,3]dioxol-4-one 
• 1361582-33-3 7-hexyl-5-methyl-1-tosyl-2,3,4,5-tetrahydro-1H-indole 
• 35660-91-4 (Z)-1-phenylbut-2-en-1-one 
• 35660-91-4 (E)-1-phenyl-2-buten-1-one 

Relevant articles and documents

Ynamide Carbopalladation: A Flexible Route to Mono-, Bi- and Tricyclic Azacycles

Bromoenynamides represent precursors to a diversity of azacycles by a cascade sequence of carbopalladation followed by cross-coupling/electrocyclization, or reduction processes. Full details of our investigations into intramolecular ynamide carbopalladation are disclosed, which include the first examples of carbopalladation/cross-coupling reactions using potassium organotrifluoroborate salts; and an understanding of factors influencing the success of these processes, including ring size, and the nature of the coupling partner. Additional mechanistic observations are reported, such as the isolation of triene intermediates for electrocyclization. A variety of hetero-Diels-Alder reactions using the product heterocycles are also described, which provide insight into Diels-Alder regioselectivity.

The Stannyl-Cupration of Acetylenes and the Reaction of the Intermediate Cuprates with Electrophiles as a Synthesis of Substituted Vinylstannanes

Stannyl-cupration of acetylenes followed by electrophilic attack with a variety of electrophiles gives vinylstannanes.

Process for production of ceophalosporins

Cephalosporin and 1-carba(1-dethia)cephalosporin antibiotics substituted in the 3-position with, inter alia, alkyl, alkenyl and alkynyl, are provided via process comprising conversion of a cephalosporin or 1-carba(1-dethia)-3-cephem substituted in the 3-p