120635-31-6

Basic information

• Product Name: 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 8-oxo-7-[(phenylacetyl)amino]-3-(1Z)-1-propenyl-, (4-methoxyphenyl)methyl ester, (6R,7R)-
• CAS NO: 120635-31-6
• Molecular Formula: C26H26N2O5S
• Molecular Weight: 478.569
• Mol File: 120635-31-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 8-oxo-7-[(phenylacetyl)amino]-3-(1Z)-1-propenyl-, (4-methoxyphenyl)methyl ester, (6R,7R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 8-oxo-7-[(phenylacetyl)amino]-3-(1Z)-1-propenyl-, (4-methoxyphenyl)methyl ester, (6R,7R)-(120635-31-6)
• EPA Substance Registry System: 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 8-oxo-7-[(phenylacetyl)amino]-3-(1Z)-1-propenyl-, (4-methoxyphenyl)methyl ester, (6R,7R)-(120635-31-6)

Safety Data

• Hazardous Substances Data: 120635-31-6(Hazardous Substances Data)

Upstream product

• 123054-30-8 (7R)-7-[(phenylacetyl)amino]-3-trifluoromethanesulfonyloxy-3-cephem-4-carboxylate, 4-methoxybenzyl ester 
• 66680-84-0 (Z)-1-propenyltributyltin 
• 66680-84-0 tributyl(propenyl)tin 
• 139472-60-9 2-((2R,3R)-2-Benzenesulfonylsulfanyl-4-oxo-3-phenylacetylamino-azetidin-1-yl)-buta-2,3-dienoic acid 4-methoxy-benzyl ester 
• 75-07-0 acetaldehyde 
• 123054-30-8 (6R,7R)-8-Oxo-7-phenylacetylamino-3-trifluoromethanesulfonyloxy-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-methoxy-benzyl ester 

Relevant articles and documents

PROCESSES FOR THE PREPARATION OF CEPHEM DERIVATIVES

Provided is a process for preparing a compound of formula 1 or its salt, which includes reacting a compound of formula 2 with a compound of formula 3 in the presence of a base.

A facile synthesis of C(3)-alkenyl substituted cephems through addition-cyclization of allenecarboxylates derived from penicillin

A short-cut route to cephalosporins bearing alkenyl substituents on the C(3)-position through copper(I) chloride-promoted Michael-type addition of alkenyltributyltins to allenecarboxylates, derived from penicillin, is described.

Palladium in Cephalosporin Chemistry: Mild Triflate Couplings in the Absence of Phosphines and Halide Donors

Palladium catalyzed triflate-organostannane couplings are shown to proceed in a very mild manner in the absence of added phosphine and halide reagents.This protocol has been demonstrated for 3-trifloxycephems and vinyltriflates.