69843-08-9

Basic information

• Product Name: Benzene, 1-methoxy-4-[1-(trifluoromethyl)ethenyl]-
• CAS NO: 69843-08-9
• Molecular Formula: C10H9F3O
• Molecular Weight: 202.176
• Mol File: 69843-08-9.mol
• Article Data: 29

Chemical Properties

• CAS DataBase Reference: Benzene, 1-methoxy-4-[1-(trifluoromethyl)ethenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-methoxy-4-[1-(trifluoromethyl)ethenyl]-(69843-08-9)
• EPA Substance Registry System: Benzene, 1-methoxy-4-[1-(trifluoromethyl)ethenyl]-(69843-08-9)

Safety Data

• Hazardous Substances Data: 69843-08-9(Hazardous Substances Data)

Upstream product

• 76953-96-3 1-(4-methoxyphenyl)-1-(trifluoromethyl)ethanol 
• 711-38-6 4'-methoxy-2,2,2-trifluoroacetophenone 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 1514-82-5 2-bromo-3,3,3-trifluoropropene 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 1541177-41-6 1,1,1-trifluoro-2-(4-methoxyphenyl)-3-(trimethylsilyl)propan-2-ol 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 357274-85-2 α-(trifluoromethyl)ethenyl boronic acid 
• 124-63-0 methanesulfonyl chloride 
• 2730-62-3 2-chloro-1,1,1-trifluoropropene 
• 5720-07-0 4-methoxyphenylboronic acid 
• 2065-66-9 methyl-triphenylphosphonium iodide 
• 696-62-8 para-iodoanisole 
• 69843-10-3 1-chloro-4-(1,1,1-trifluoroprop-2-en-2-yl)benzene 

Downstream Products

• 76953-96-3 1-(4-methoxyphenyl)-1-(trifluoromethyl)ethanol 
• 1079398-12-1 1-(1,1-difluoro-3-phenylprop-1-en-2-yl)-4-methoxybenzene 
• 1433608-74-2 tert-butyl 3-fluoro-4-(p-methoxyphenyl)-1H-pyrazole-1-carboxylate 
• 1433608-20-8 N’-[3,3-difluoro-2-(p-methoxyphenyl)prop-2-en-1-yl]-N’-tert-butoxycarbonyl-p-toluenesulfonohydrazide 
• 1433607-86-3 C₁₅H₂₀F₂N₂O₃ 
• 1541177-63-2 3,3,3-trifluoro-2-(4-methoxyphenyl)propane-1,2-diol 
• 1541177-61-0 1-(1-bromo-3,3,3-trifluoroprop-1-en-2-yl)-4-methoxybenzene 
• 1541177-64-3 1-(1-bromo-3,3,3-trifluoroprop-1-en-2-yl)-4-methoxybenzene 
• 1431983-72-0 1-(2,2-difluoro-1-(trifluoromethyl)cyclopropyl)-4-methoxybenzene 
• 1541177-62-1 1-(3,3-difluoro-2-(4-methoxyphenyl)allyl)piperidine 
• 1638968-66-7 (3-fluoro-4-(4-methoxyphenyl)cyclopenta-1,3-diene-1,2-diyl)dibenzene 
• 1180131-08-1 (R)-3,3,3-trifluoro-2-(4-methoxyphenyl)propan-1-ol 

Relevant articles and documents

Electroreductive Cross-Coupling of Trifluoromethyl Alkenes and Redox Active Esters for the Synthesis of Gem-Difluoroalkenes

An electroreductive access to gem-difluoroalkenes has been developed through the decarboxylative/defluorinative coupling of N-hydroxyphtalimides esters and α-trifluoromethyl alkenes. The electrolysis is performed under very simple reaction conditions in a

Photoredox/Hydrogen Atom Transfer Cocatalyzed C-H Difluoroallylation of Amides, Ethers, and Alkyl Aldehydes

Herein, we report a method that combines hydrogen atom transfer and photoredox catalysis to achieve the dehydrogenative difluoroallylation of amides, ethers, and alkyl aldehydes. This operationally convenient method transforms a broad scope of substrates into the corresponding gem-difluoroalkenes via the construction of C(sp3)-C(sp3) or C(sp3)-C(sp2) bonds. Excellent functional group compatibility and high selectivity make this method have a wide range of substrate types and render it suitable for late-stage modification of pharmaceutical intermediates.

Site-Selective Defluorinative sp3C-H Alkylation of Secondary Amides

A site-selective defluorinative sp3 C-H alkylation of secondary amides that rapidly and reliably incorporates gem-difluoroalkene motifs into previously unfunctionalized sp3 sites is disclosed. This protocol is distinguished by its mild conditions, wide scope, and exquisite site-selectivity, thus unlocking a new platform to introduce carbonyl isosteres at saturated hydrocarbon sites.