65253-31-8

Basic information

• Product Name: 1-Hydroxy-8-chloronaphthalene
• Synonyms: 1-Hydroxy-8-chloronaphthalene
• CAS NO: 65253-31-8
• Molecular Formula: C₁₀H₇ClO
• Molecular Weight: 178.61498
• Mol File: 65253-31-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 331.9°C at 760 mmHg
• Flash Point: 154.5°C
• Appearance: /
• Density: 1.333g/cm³
• Vapor Pressure: 7.84E-05mmHg at 25°C
• Refractive Index: 1.684
• PKA: 8.63±0.40(Predicted)
• CAS DataBase Reference: 1-Hydroxy-8-chloronaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Hydroxy-8-chloronaphthalene(65253-31-8)
• EPA Substance Registry System: 1-Hydroxy-8-chloronaphthalene(65253-31-8)

Safety Data

• Hazardous Substances Data: 65253-31-8(Hazardous Substances Data)

Usage

Description

1-Hydroxy-8-chloronaphthalene is a chemical compound belonging to the naphthalene derivatives family. It features a naphthalene ring with a hydroxyl group at the first position and a chlorine atom at the eighth position, contributing to its unique chemical properties and applications.

Uses

Used in Pharmaceutical Industry:
1-Hydroxy-8-chloronaphthalene is used as an intermediate in the synthesis of various organic compounds and pharmaceuticals for its ability to facilitate the creation of diverse medicinal agents.
Used in Dye and Pigment Production:
1-Hydroxy-8-chloronaphthalene is utilized in the production of dyes and pigments, capitalizing on its chemical structure to yield a range of colorants for different applications.
Environmental Considerations:
Due to its aromatic nature, 1-Hydroxy-8-chloronaphthalene is a potential environmental contaminant. It may pose health risks if not handled and disposed of properly, necessitating the adherence to safety guidelines and regulations in its use and disposal.

InChI:InChI=1/C10H7ClO/c11-8-5-1-3-7-4-2-6-9(12)10(7)8/h1-6,12H

Upstream product

• 602-37-9 1-chloro-8-nitro-naphthalene 
• 90-13-1 1-Chloronaphthalene 
• 41908-14-9 1-chloro-8-methoxynaphthalene 
• 7732-18-5 water 
• 86-57-7 1-Nitronaphthalene 
• 2216-69-5 1-Methoxynaphthalene 

Relevant articles and documents

Carbonyl Oxide Chemistry. The NIH Shift

Benzophenone oxide has been shown to oxidize 1-chloronaphthalene and p-xylene with accompanying NIH shift of chlorine and methyl, respectively.Similar oxidation of toluene leads to a mixture of o-,p-, and m-cresols while N-acetyl-L-phenylalanine ethyl ester is oxidized to the corresponding tyrosine derivative.The results are discussed in terms of their relationship to the "activation" of polycyclic aromatic hydrocarbons in polluted atmospheres and the possible production of mutagens/carcinogens.