6082-66-2 Usage
Description
3,4,6-Trichloropyridazine is a chemical compound with the molecular formula C4HN3Cl3. It is a derivative of pyridazine, a heterocyclic aromatic compound, and features three chlorine atoms attached to the 3rd, 4th, and 6th positions of the pyridazine ring. 3,4,6-Trichloropyridazine is known for its potential applications in various fields, particularly in pharmaceutical and chemical research.
Uses
Used in Pharmaceutical Research:
3,4,6-Trichloropyridazine is used as a research compound for studying chloropyridazine derivatives, which have shown potential as human rhinovirus capsid-binding inhibitors. These inhibitors can play a crucial role in the development of antiviral drugs targeting the human rhinovirus, a common cause of the common cold and other respiratory infections.
In this application, 3,4,6-Trichloropyridazine serves as a key intermediate or starting material in the synthesis of more complex chloropyridazine derivatives with improved antiviral properties. The study of these derivatives can lead to a better understanding of their interaction with the human rhinovirus capsid, ultimately contributing to the design of more effective antiviral therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 6082-66-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,0,8 and 2 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 6082-66:
(6*6)+(5*0)+(4*8)+(3*2)+(2*6)+(1*6)=92
92 % 10 = 2
So 6082-66-2 is a valid CAS Registry Number.
InChI:InChI=1/C4HCl3N2/c5-2-1-3(6)8-9-4(2)7/h1H
6082-66-2Relevant articles and documents
Methods for treating neisseria gonorrhoeae infection with substituted 1,2-dihydro-2A,5,8A-triazaacenaphthylene-3,8-diones
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Page/Page column 137, (2020/07/21)
The present invention relates to methods for treating Neisseria Gonorrhoeae infection which comprises administering to a subject in need thereof novel 1,2-dihydro-2a,5,8a-triazaacenaphthylene-3,8-dione compounds: or pharmaceutically acceptable salts thereof and/or corresponding pharmaceutical compositions.
THYROID HORMONE RECEPTOR AGONISTS AND USES THEREOF
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Paragraph 00333; 00334; 00383, (2020/01/08)
Described herein are methods and compositions for the treatment of conditions, diseases, or disorders associated with thyroid hormone receptor activity. The methods and compositions disclosed herein include the use of at least one thyroid hormone receptor agonist.
Access to 4-alkylaminopyridazine derivatives via nitrogen-assisted regioselective pd-catalyzed reactions
Blaise, Emilie,Kümmerle, Arthur E.,Hammoud, Hassan,De Arajo-Jnior, Jo Xavier,Bihel, Frdric,Bourguignon, Jean-Jacques,Schmitt, Martine
, p. 10311 - 10322 (2015/02/19)
3-Substituted, 6-substituted, and unsymmetrical 3,6-disubstituted 4-alkylaminopyridazines were prepared from a sequence of three chemo- and regioselective reactions combining amination and palladium-catalyzed cross-coupling reactions, such as reductive dehalogenation and Suzuki-Miyaura reactions. Extension of the methodology to Sonogashira reaction yielded a novel class of 3-substituted pyrrolopyridazines.