15456-86-7

Basic information

• Product Name: Pyridazine, 3,6-dione, 4-bromo-1,2-dihydro-
• Synonyms: 4-Bromo-6-Hydroxy-3(2H)-Pyridazinone;Pyridazine, 3,6-dione, 4-bromo-1,2-dihydro-;3(2H)-Pyridazinone, 4-bromo-6-hydroxy-;4-Bromo-3-hydroxy-6-pyridazinone;4-Bromo-1,2-dihydropyridazine-3,6-dione;Nsc79701
• CAS NO: 15456-86-7
• Molecular Formula: C₄H₃BrN₂O₂
• Molecular Weight: 190.99
• EINECS: 200-001-2
• Mol File: 15456-86-7.mol
• Article Data: 27

Chemical Properties

• Appearance: /
• Density: 1.965 g/cm³
• Refractive Index: 1.59
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 7?+-.0.40(Predicted)
• CAS DataBase Reference: Pyridazine, 3,6-dione, 4-bromo-1,2-dihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridazine, 3,6-dione, 4-bromo-1,2-dihydro-(15456-86-7)
• EPA Substance Registry System: Pyridazine, 3,6-dione, 4-bromo-1,2-dihydro-(15456-86-7)

Safety Data

• Hazardous Substances Data: 15456-86-7(Hazardous Substances Data)

Usage

Description

Pyridazine, 3,6-dione, 4-bromo-1,2-dihydro-, also known as 4-bromo-1,2-dihydro-3,6-pyridazinedione, is a heterocyclic chemical compound with the molecular formula C4H3BrN2O2. It features a pyridazine ring fused with a 1,2-dihydro-3,6-dione moiety and a bromine atom. Pyridazine, 3,6-dione, 4-bromo-1,2-dihydrohas potential pharmaceutical applications and is utilized as an intermediate in the synthesis of pharmaceutical drugs. Additionally, it serves as a building block in organic synthesis and research for creating more complex compounds. Due to its potential health and environmental hazards, it is crucial to handle this chemical with care.

Uses

Used in Pharmaceutical Industry:
Pyridazine, 3,6-dione, 4-bromo-1,2-dihydrois used as an intermediate in the synthesis of pharmaceutical drugs for its potential medicinal properties. Its unique structure allows for the development of new drug candidates with specific therapeutic effects.
Used in Organic Synthesis:
In the field of organic synthesis, Pyridazine, 3,6-dione, 4-bromo-1,2-dihydrois employed as a building block to create more complex compounds. Its heterocyclic nature and functional groups enable the formation of various derivatives with diverse applications in chemical research and development.
Used in Research:
Pyridazine, 3,6-dione, 4-bromo-1,2-dihydrois utilized in research settings to explore its chemical properties, reactivity, and potential applications in the development of new materials and compounds. Its unique structure and functional groups make it an interesting subject for scientific investigation and experimentation.

InChI:InChI=1/C4H3BrN2O2/c5-2-1-3(8)6-7-4(2)9/h1H,(H,6,8)(H,7,9)

Upstream product

• 5926-51-2 bromomaleic anhydride 
• 10034-93-2 hydrazinium sulfate 

Downstream Products

• 6082-66-2 3,4,6-trichloropyridazine 
• 943025-98-7 4-bromo-2-{[4-(methyloxy)phenyl]methyl}-6-({[4-(methyloxy)phenyl]methyl}oxy)-3(2H)-pyridazinone 
• 943025-99-8 5-bromo-2-{[4-(methyloxy)phenyl]methyl}-6-({[4-(methyloxy)phenyl]methyl}oxy)-3(2H)-pyridazinone 
• 202931-70-2 3,6-dichloro-4-(pyridin-4-yl)pyridazine 
• 10344-42-0 4-bromo-3,6-dichloro-pyridazine 
• 1003944-29-3 C₄HBrCl₂N₂ 
• 910229-65-1 5-bromo-6-oxo-1,6-dihydropyridazin-3-yl 2,4,6-triisopropylbenzenesulfonate 

Relevant articles and documents

Methods for treating neisseria gonorrhoeae infection with substituted 1,2-dihydro-2A,5,8A-triazaacenaphthylene-3,8-diones

The present invention relates to methods for treating Neisseria Gonorrhoeae infection which comprises administering to a subject in need thereof novel 1,2-dihydro-2a,5,8a-triazaacenaphthylene-3,8-dione compounds: or pharmaceutically acceptable salts thereof and/or corresponding pharmaceutical compositions.

A general approach to access 5,6-dihydroindolo-naphthyridine ring system

We report a general approach for the synthesis of 5,6-dihydroindolo-naphthyridine ring system via an intramolecular cyclization of the indole NH to an alkene moiety as the key step.

Access to 4-alkylaminopyridazine derivatives via nitrogen-assisted regioselective pd-catalyzed reactions

3-Substituted, 6-substituted, and unsymmetrical 3,6-disubstituted 4-alkylaminopyridazines were prepared from a sequence of three chemo- and regioselective reactions combining amination and palladium-catalyzed cross-coupling reactions, such as reductive dehalogenation and Suzuki-Miyaura reactions. Extension of the methodology to Sonogashira reaction yielded a novel class of 3-substituted pyrrolopyridazines.