6017-59-0

Basic information

• Product Name: 4,5-Isoxazoledione, 3-methyl-, 4-(phenylhydrazone)
• CAS NO: 6017-59-0
• Molecular Formula: C10H9N3O2
• Molecular Weight: 203.2
• Mol File: 6017-59-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 4,5-Isoxazoledione, 3-methyl-, 4-(phenylhydrazone)(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-Isoxazoledione, 3-methyl-, 4-(phenylhydrazone)(6017-59-0)
• EPA Substance Registry System: 4,5-Isoxazoledione, 3-methyl-, 4-(phenylhydrazone)(6017-59-0)

Safety Data

• Hazardous Substances Data: 6017-59-0(Hazardous Substances Data)

Upstream product

• 6020-14-0 3-hydroxyimino-butyric acid anilide 
• 10475-63-5 3-oxo-2-(phenylhydrazono)butyric acid ethyl ester 
• 27991-08-8 N-acetoacetylphenylhydroxyloamine 
• 60083-15-0 ethyl (Z)-3-oxo-2-(2-phenylhydrazono)butanoate 
• 132934-86-2 5-Acetyl-3-phenyl-2-[(Z)-phenylimino]-2,3-dihydro-[1,3,4]thiadiazin-6-one 
• 5462-33-9 ethyl phenylazoacetoacetate 
• 100-34-5 benzene diazonium chloride 
• 141-97-9 ethyl acetoacetate 
• 62-53-3 aniline 
• 2684-02-8 benzenediazonium 
• 102-01-2 N-phenylacetoacetamide 
• 1517-96-0 3-methyl-5-isoxazolone 
• 132934-83-9 5-Acetyl-3-phenyl-2-thioxo-2,3-dihydro-[1,3,4]thiadiazin-6-one 
• 132934-80-6 C₁₃H₁₃N₂O₃S₂^(1-)*Na⁽¹⁺⁾ 

Downstream Products

• 19374-75-5 3-methyl-1-phenylpyrazole-4,5-dione 4-phenylhydrazone 
• 27301-71-9 2,3-bis-phenylhydrazono-butyric acid 
• 51450-88-5 3-methyl-4-phenylazo-2-propionyl-2H-isoxazol-5-one 
• 51450-74-9 2-benzoyl-3-methyl-4-phenylazo-2H-isoxazol-5-one 
• 51450-82-9 3-methyl-2-(4-nitro-benzoyl)-4-phenylazo-2H-isoxazol-5-one 
• 51450-92-1 2-but-2-enoyl-3-methyl-4-phenylazo-2H-isoxazol-5-one 
• 51450-86-3 2-acetyl-3-methyl-4-phenylazo-2H-isoxazol-5-one 
• 51450-90-9 2-butyryl-3-methyl-4-phenylazo-2H-isoxazol-5-one 
• 1747-61-1 2,3-dimethyl-4-phenylazoisoxazol-5-one 
• 5777-08-2 4-(N-methylphenylhydrazono)-3-methylisoxazol-5-one 
• 27843-96-5 (1E)-1-(2-phenylhydrazin-1-ylidene)propan-2-one 
• 51039-50-0 5-methyl-2-phenyl-2H-[1,2,3]triazole 
• 38482-38-1 methylglyoxal 2-oxime 1-phenylhydrazone 
• 7664-41-7 ammonia 

Relevant articles and documents

Aqueous phase synthesis, crystal structure and antimicrobial activity of 4-(substituted phenylazo)-3-methyl-4H-isoxazol-5-one azo dyes

3-Methyl-4H-isoxazol-5-one was synthesized at room temperature by simple stirring method from ethyl acetoacetate and hydroxylamine hydrochloride in aqueous medium and coupled with diazotized substituted amine to form series of 4-(substituted phenylazo)-3-methyl-4H-isoxazol-5-ones through green chemistry. All the compounds formed were characterized by IR, 1H and 13C NMR spectroscopy, MS and elemental analysis. Crystal structure of novel 4-(4-fluorophenylazo)-3-methyl-4H-isoxazol-5-one was determined by the X-ray diffraction. Antibacterial and antifungal activity was studied against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus pyogenus and Candida albicans, Aspergillus niger, Aspergillus clavatus, respectively. All synthesized compounds were found to be active against a gram-positive bacterium Staphylococcus aureus. Two compounds showed antifungal activity against Candida albicans close to standard greseofulvin.

Synthesis and ring transformation of a few substituted 3,6-dihydro-2H-6-oxo-1,3,4-thiadiazines and evaluation of their antibacterial activity

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An HMO study of the azo-hydrazone tautomerism in diazonium coupling products of 5-isoxazolones

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