5995-42-6

Basic information

• Product Name: [[(2-hydroxyethyl)imino]bis(methylene)]bisphosphonic acid
• Synonyms: [[(2-hydroxyethyl)imino]bis(methylene)]bisphosphonic acid;Phosphonic acid, (2-hydroxyethyl)iminobis(methylene)bis-;ethanolaminedi(methylenephosphonic acid);2-[Bis(phosphonomethyl)amino]ethanol;2-Hydroxyethylbis(phosphonomethyl)amine;2-Hydroxyethyliminobis(methylene phosphonic acid);2-Hydroxyethyliminodimethanephosphonic acid;Einecs 227-833-4
• CAS NO: 5995-42-6
• Molecular Formula: C4H13NO7P2
• Molecular Weight: 249.096042
• EINECS: 227-833-4
• Product Categories: Water treatment
• Mol File: 5995-42-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 612.637 °C at 760 mmHg
• Flash Point: 324.312 °C
• Appearance: /
• Density: 1.81 g/cm³
• Vapor Pressure: 1.43E-17mmHg at 25°C
• Refractive Index: 1.578
• CAS DataBase Reference: [[(2-hydroxyethyl)imino]bis(methylene)]bisphosphonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: [[(2-hydroxyethyl)imino]bis(methylene)]bisphosphonic acid(5995-42-6)
• EPA Substance Registry System: [[(2-hydroxyethyl)imino]bis(methylene)]bisphosphonic acid(5995-42-6)

Safety Data

• Hazardous Substances Data: 5995-42-6(Hazardous Substances Data)

Usage

Description

[[(2-hydroxyethyl)imino]bis(methylene)]bisphosphonic acid, also known as HEDP, is a versatile organic compound characterized by its colorless and odorless liquid form, which is soluble in water. It is recognized for its exceptional ability to sequester metal ions, making it a prominent chelating agent and scale inhibitor in various industrial applications.

Uses

Used in Detergent Production:
HEDP is utilized as a chelating agent and scale inhibitor in the production of detergents, ensuring the effective removal of metal ions that could otherwise cause scale buildup and reduce cleaning performance.
Used in Water Treatment:
In the water treatment industry, HEDP serves as a critical component for preventing scale formation and controlling corrosion in water systems, thereby enhancing the efficiency and longevity of water infrastructure.
Used in Metal Treatment Processes:
HEDP is employed in metal treatment processes to inhibit scale and corrosion, protecting metal surfaces and equipment from damage and extending their service life.
Used in Oil and Gas Industry:
Within the oil and gas sector, HEDP is applied as a corrosion inhibitor, safeguarding pipelines and equipment from the corrosive effects of the substances they handle, thus ensuring operational reliability and safety.
Used in Personal Care Product Manufacturing:
HEDP is also used in the production of personal care products, where it helps to prevent scale buildup and maintain product quality and efficacy.
Overall, [[(2-hydroxyethyl)imino]bis(methylene)]bisphosphonic acid, or HEDP, is a multifunctional compound that plays a significant role across different industries, primarily due to its chelating, scale inhibition, and corrosion prevention properties. Its safe use is regulated by environmental agencies, ensuring its application aligns with ecological standards.

InChI:InChI=1/C4H13NO7P2/c6-2-1-5(3-13(7,8)9)4-14(10,11)12/h6H,1-4H2,(H2,7,8,9)(H2,10,11,12)

Upstream product

• 50-00-0 formaldehyd 
• 141-43-5 ethanolamine 
• 57441-12-0 2-chloroethylamine-N,N-bis(methylenephosphonic acid) 
• 56-40-6 glycine 
• 302-72-7 rac-Ala-OH 
• 52-90-4 L-Cysteine 
• 68-11-1 mercaptoacetic acid 
• 124-02-7 diallylamine 
• 107-10-8 propylamine 
• 2617-47-2 hydroxymethylphosphonic acid 
• 2002-24-6 2-amino-ethanol hydrochloride 
• 17261-34-6 (iminobismethylene)bisphosphonic acid 
• 107-07-3 2-chloro-ethanol 

Relevant articles and documents

MOLECULAR STRUCTURE OF 4-(PHOSPHONOMETHYL)-2-HYDROXY-2-OXO-1,4,2-OXAZAPHOSPHORINANE

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Intramolecular cyclization of 1,3-diamino-2-hydroxypropan-N,N,ń,ń-tetrakis(methylphosphonic acid) upon phosphonomethylation of 1,3-diaminopropan-2-ol

Phosphonomethylation of 1,3-diaminopropan-2-ol affords the mixture of 1,3-diamino-2-hydroxypropan-N,N,ń,ń-tetrakis(methylphosphonic acid) (1) with its cyclic ether, viz., [(6-[bis(phosphonomethyl)amino]methyl-2-hydroxy-2-oxido-1,4,2-oxazaphosphinan-4-yl)methyl]phosphonic acid (2), but not 1, as assumed earlier.

Process for the manufacture of alkylamino alkylene phosphonic acids

A process for the manufacture of alkylamino alkylene phosphonic acids is disclosed. In detail, a specific phosphonate is reacted with an agent selected to yield an alkylamino moiety substituted by a radical selected from OH, OR', NH2, NHR', N(R')2, NH, N, S, S-S and SH in aqueous alkaline medium having a pH of 8 or higher at a temperature of 0°C or higher.

PHOSPHONOMETHYLATION OF AMINOALKANOLS PREPARATION OF 4-(PHOSPHONOMETHYL)-2-HYDROXY-2-OXO-1,4,2-OXAZAPHOSPHORINANES

Treatment of aminoalkanols 1 with phosphorous acid and formaldehyde in presence of conc. hydrochloric acid gave mixtures of dimethylene diphosphonic acids 3 and 4-(phosphonomethyl)-2-hydroxy-2-oxo-1,4,2-oxazaphosphorinanes 2 from which 2 were isolated as crystalline solids.Similiar treatment of 2-amino-2-methyl-1,3-propanediol 8 gave a complex mixture from which dimethylene diphosphonic acid of 5-amino-5-methyl-1,3-dioxane 9 was isolated. 2-Amino-ethanediol, when subjected to phosphonomethylation, gave an unexpected novel quarternary nitrogen product 11.N-Alkylaminoalkanols 4 on phosphonomethylation gave 3:1 mixtures of methane phosphonic acid 6 and N-alkyl-2-hydroxy-2-oxo-1,4,2-oxazaphosphorinane 5.Treatment of the crude mixtures of 5 and 6 with aqueous sodium hydroxide gave disodium salts of methanephosphonic acid 7.The ratio of the cyclic to the open chain structures obtained as well as the formation of any unexpected novel products is dependent on the structure of the aminoalkanol that is phosphonomethylated.The 1H, 13C and 31P spectra are reported for all new compounds.