5470-70-2 Usage
Description
Methyl 6-methylnicotinate, also known as Methyl 6-methylpyridine-3-carboxylate, is an organic compound with the chemical formula C7H7NO2. It is a brown solid and is used in various applications, particularly in the pharmaceutical and chemical synthesis industries.
Uses
Used in Pharmaceutical Industry:
Methyl 6-methylnicotinate is used as a treatment agent for Central Nervous System (CNS) disorders. It functions through the inhibition of D-amino acid oxidase and D-aspartate oxidase, which are enzymes involved in the metabolism of D-amino acids in the brain. This inhibition can help alleviate the symptoms of certain CNS disorders.
Used in Chemical Synthesis Studies:
Methyl 6-methylnicotinate may also be utilized in chemical synthesis studies, where it can serve as a starting material or intermediate for the development of new compounds with potential applications in various fields, including pharmaceuticals, agrochemicals, and materials science.
Synthesis Reference(s)
Journal of the American Chemical Society, 97, p. 4409, 1975 DOI: 10.1021/ja00848a053
Check Digit Verification of cas no
The CAS Registry Mumber 5470-70-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,7 and 0 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 5470-70:
(6*5)+(5*4)+(4*7)+(3*0)+(2*7)+(1*0)=92
92 % 10 = 2
So 5470-70-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H9NO2/c1-6-3-4-7(5-9-6)8(10)11-2/h3-5H,1-2H3
5470-70-2Relevant articles and documents
60Co γ-Irradiation: Homolytic Alkylation of Methyl Nicotinate
Newkome, George R.,Marston, Charles R.
, p. 4162 - 4163 (1985)
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Nickel-Catalyzed Oxidative Decarboxylative Annulation for the Synthesis of Heterocycle-Containing Phenanthridinones
Honeycutt, Aaron P.,Hoover, Jessica M.
supporting information, p. 7216 - 7219 (2018/11/23)
A nickel-catalyzed oxidative decarboxylative annulation reaction of simple benzamides and (hetero)aromatic carboxylates has been developed. This reaction provides access to a large array of phenanthridinones and their heterocyclic analogues, highlighting the utility and versatility of oxidative decarboxylative coupling strategies for C-C bond formation.
P2X3 AND/OR P2X2/3 COMPOUNDS AND METHODS
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Paragraph 0152; 0153; 0154, (2015/07/07)
The present application provides novel compounds and methods for preparing and using these compounds. In one embodiment, the compounds are of the structure of formula (I), wherein R1-R4 are defined herein. In a further embodiment, these compounds are useful in method for regulating one or both of the P2X3 or P2X2/3 receptors. In another embodiment, these compounds are useful for treating pain in patients by administering one or more of the compounds to a patient.