1421227-97-5 Usage
Description
1-(6-methylpyridin-3-yl)-2-(4-[2-(6-methylpyridin-3-yl)-2-oxoethyl]phenylsulfonyl)ethanone is a complex organic compound characterized by its unique molecular structure. It is an impurity found in Etoricoxib (E934100), which is a specific inhibitor of COX-2, an enzyme involved in the production of prostaglandins that contribute to inflammation and pain.
Uses
Used in Pharmaceutical Industry:
1-(6-methylpyridin-3-yl)-2-(4-[2-(6-methylpyridin-3-yl)-2-oxoethyl]phenylsulfonyl)ethanone is used as an impurity in the production of Etoricoxib (E934100) for its role in the pharmaceutical industry. As an impurity, it is essential to monitor and control its presence to ensure the safety, efficacy, and quality of the final drug product.
Application Reason:
The presence of this impurity in Etoricoxib is significant because it can impact the drug's overall performance, safety, and regulatory compliance. By understanding and controlling the levels of this impurity, pharmaceutical companies can ensure that Etoricoxib maintains its effectiveness as a COX-2 inhibitor and minimizes potential side effects or adverse reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 1421227-97-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,1,2,2 and 7 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1421227-97:
(9*1)+(8*4)+(7*2)+(6*1)+(5*2)+(4*2)+(3*7)+(2*9)+(1*7)=125
125 % 10 = 5
So 1421227-97-5 is a valid CAS Registry Number.
1421227-97-5Relevant articles and documents
Novel process for the preparation of 1-(6-methylpyridin-3-yl)-2-[4-(methylsulfonyl)phenyl]ethanone, an intermediate of etoricoxib.
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, (2013/03/26)
The present invention refers to a novel process for the preparation of 1-(6-methylpyridin-3-yl)-2-[4-(methylsulfonyl)phenyl]ethanone, an intermediate of the synthesis of Etoricoxib, an active ingredient on which the Arcoxia drug is based.
