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5470-44-0

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5470-44-0 Usage

Description

3-bromooxolane-2,5-dione is a brominated derivative of oxolane-2,5-dione with the molecular formula C4H3BrO3. It is a white to off-white crystalline solid and belongs to the class of organic compounds known as delta lactones. This chemical compound is commonly used in organic synthesis and pharmaceutical research due to its unique structure and reactivity, making it a versatile intermediate in the synthesis of various biologically active compounds. It has been studied for its potential pharmacological and medicinal applications, serving as an important building block in the development of new drugs and pharmaceuticals.

Uses

Used in Organic Synthesis:
3-bromooxolane-2,5-dione is used as a versatile intermediate in organic synthesis for the preparation of various biologically active compounds. Its unique structure and reactivity make it a valuable building block in the development of new chemical entities.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 3-bromooxolane-2,5-dione is used as a key intermediate in the synthesis of drugs and pharmaceuticals. Its potential pharmacological and medicinal applications have been studied, contributing to the discovery and development of novel therapeutic agents.
Used in Drug Development:
3-bromooxolane-2,5-dione is employed as a crucial component in drug development, where its unique properties and reactivity are utilized to create new drugs with improved efficacy and safety profiles. Its role as a building block in the synthesis of biologically active compounds aids in the advancement of pharmaceutical research and innovation.

Check Digit Verification of cas no

The CAS Registry Mumber 5470-44-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,7 and 0 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 5470-44:
(6*5)+(5*4)+(4*7)+(3*0)+(2*4)+(1*4)=90
90 % 10 = 0
So 5470-44-0 is a valid CAS Registry Number.
InChI:InChI=1/C4H3BrO3/c5-2-1-3(6)8-4(2)7/h2H,1H2

5470-44-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-bromooxolane-2,5-dione

1.2 Other means of identification

Product number -
Other names 2,5-Furandione, 3-bromodihydro-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5470-44-0 SDS

5470-44-0Relevant articles and documents

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Welling et al.

, p. 31,33 (1974)

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Nanoprecipitation of biocompatible poly(Malic acid) derivative, its ability to encapsulate a molecular photothermal agent and photothermal properties of the resulting nanoparticles

Bellec, Nathalie,Camerel, Franck,Cammas-Marion, Sandrine,Pluta, Jean-Baptiste,Vargas Guerrero, Marian Gabriela

, (2021/12/27)

Biocompatible nanoparticles (NPs) of hydrophobic poly(benzyl malate) (PMLABe) were prepared by nanoprecipitation. The influence of nanoprecipitation parameters (initial PMLABe, addition rate, organic solvent/water ratio and stirring speed) were studied to optimize the resulting formulations in terms of hydrodynamic diameter (Dh) and dispersity (PDI). PMLABe NPs with a Dh of 160 nm and a PDI of 0.11 were isolated using the optimized nanoprecipitation conditions. A hydrophobic near infra-red (NIR) photothermally active nickel-bis(dithiolene) complex (Ni8C12) was then encapsulated into PMLABe NPs using the optimized nanoprecipitation conditions. The size and encapsulation efficiency of the NPs were measured, revealing that up to 50 weight percent (wt%) of Ni8C12 complex can efficiently be encapsulated with a slight increase in Dh of the corresponding Ni8C12-loaded NPs. Moreover, we have shown that NP encapsulating Ni8C12 were stable under storage conditions (4?C) for at least 10 days. Finally, the photothermal properties of Ni8C12-loaded NPs were evaluated and a high photothermal efficiency (62.7 ± 6.0%) waswas measured with NPs incorporating 10 wt% of the Ni8C12 complex.

Synthesis and study of the cancer cell growth inhibitory properties of α-, γ-tocopheryl and γ-tocotrienyl 2-phenylselenyl succinates

Vraka, Panayiota S.,Drouza, Chryssoula,Rikkou, Maria P.,Odysseos, Andreani D.,Keramidas, Anastasios D.

, p. 2684 - 2696 (2007/10/03)

Vitamin E succinate selenium-conjugated molecules were synthesized and their apoptogenic properties were evaluated. 4-Methyl-2-phenylselenyl succinate (4) was prepared by the reaction of sodium benzeneselenolate with 2-bromosuccinic anhydrite in methanol

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