538-74-9 Usage
Description
Dibenzyl sulphide is a colorless crystalline solid, which may appear as plates or pale beige in color. It is characterized by an unpleasant or crippling stench. This organic compound is known for its beige crystals or powder form and is utilized in various applications across different industries due to its unique chemical properties.
Uses
Used in Organic Synthesis:
Dibenzyl sulphide is used as an intermediate in the field of organic synthesis for the production of various organic compounds. Its chemical structure allows it to be a versatile building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals. Dibenzyl sulphide's reactivity and stability make it a valuable asset in creating a wide range of products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Dibenzyl sulphide is used as a key component in the development of new drugs. Its unique properties enable it to interact with biological targets, potentially leading to the discovery of novel therapeutic agents. Additionally, it may be employed in the formulation of drug delivery systems to improve the bioavailability and efficacy of existing medications.
Used in Agrochemical Industry:
Dibenzyl sulphide also finds application in the agrochemical industry, where it is used as a starting material for the synthesis of various pesticides and insecticides. Its chemical properties make it suitable for the development of compounds that can effectively control pests and diseases in agriculture, thereby contributing to increased crop yields and food security.
Used in Fragrance Industry:
Given its distinct smell, Dibenzyl sulphide can be utilized in the fragrance industry as a component in the creation of various scent profiles. Its unique odor can be blended with other compounds to develop new and innovative fragrances for the perfume, cosmetics, and personal care markets.
Used in Chemical Research:
Dibenzyl sulphide serves as a valuable research tool in the field of chemistry. It is used in various experimental setups to study reaction mechanisms, test hypotheses, and develop new methodologies. Its availability and reactivity make it an attractive candidate for researchers looking to explore new avenues in chemical science.
Synthesis Reference(s)
Canadian Journal of Chemistry, 53, p. 1480, 1975 DOI: 10.1139/v75-205Tetrahedron Letters, 27, p. 1073, 1986 DOI: 10.1016/S0040-4039(86)80051-X
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Organosulfides, such as Dibenzyl sulphide, are incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas. Many of these compounds may liberate hydrogen sulfide upon decomposition or reaction with an acid.
Fire Hazard
Dibenzyl sulphide is combustible.
Safety Profile
Moderately toxic by ingestion.When heated to decomposition it emits toxic vapors ofSOx.
Purification Methods
Crystallise the sulfide from EtOH/water (10:1), or repeatedly from Et2O. It has also been purified by chromatography on Al2O3 (pentane as eluent), then recrystallised from EtOH [Kice & Bowers J Am Chem Soc 84 2390 1962]. Dry it in a vacuum at 30o over P2O5, fused under nitrogen and re-dried. [Beilstein 6 IV 2649.]
Check Digit Verification of cas no
The CAS Registry Mumber 538-74-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,3 and 8 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 538-74:
(5*5)+(4*3)+(3*8)+(2*7)+(1*4)=79
79 % 10 = 9
So 538-74-9 is a valid CAS Registry Number.
InChI:InChI=1/C14H14S/c1-3-7-13(8-4-1)11-15-12-14-9-5-2-6-10-14/h1-10H,11-12H2
538-74-9Relevant articles and documents
Heterogeneously Ni-Pd nanoparticle-catalyzed base-free formal C-S bond metathesis of thiols
Mitamura, Kanju,Yatabe, Takafumi,Yamamoto, Kidai,Yabe, Tomohiro,Suzuki, Kosuke,Yamaguchi, Kazuya
supporting information, p. 3749 - 3752 (2021/04/21)
This study rationally designed a heterogeneously catalyzed system (i.e., using Ni-Pd alloy nanoparticles supported on hydroxyapatite (Ni-Pd/HAP) under an H2atmosphere) achieving an efficient base-free formal C-S bond metathesis of various thiolsviasuppression of the Ni catalysis deactivation.
Catalytic dehydrogenation of amines to imines and the in-situ reduction of sulfoxides into sulfides
Li, Bo,Liu, Bing,Liu, Xixi,Wang, Wei,Wang, Yanxin,Xiang, Nian,Zhang, Zehui
, p. 81 - 88 (2021/07/30)
The catalytic acceptorless dehydrogenation of primary amines into imines and H2 represents one of the most important organic transformations, and the in-situ utilization of the generated H2 for chemical reduction reactions has never
Synthesis method of dibenzyl sulfide
-
Paragraph 0008-0012, (2021/02/06)
As an important organic intermediate and a synthesis reagent, an organic sulfur compound also has unique pharmacological effects of resisting tumors, inflammation, bacteria and oxidation, preventing aging, preventing and treating cardiovascular diseases and the like. The patent develops a method for synthesizing dibenzyl sulfide without metal catalysis. In an acetonitrile solution, benzyl trifluoromethanesulfonic acid quaternary ammonium salt and sodium sulfide nonahydrate are used to synthesize dibenzyl sulfide in a wide substrate range with good to excellent yield through breakage of a carbon-nitrogen bond and generation of a carbon-sulfur bond. The method has the advantages of mild reaction conditions, simple operation, no metal, high yield, wide substrate applicability and the like.