52727-28-3

Basic information

• Product Name: 6-Hydroxyl-2-tetralone
• Synonyms: 6-hydroxyl-2-tetralone;3,4-Dihydro-6-hydroxy-1H-naphthalen-2-one;6-Hydroxy-2-tetralone;6-Hydroxyl-3,4-dihydronaphthalen-2(1H)-one;3,4-dihydro-6-hydroxy-1(2H)-naphthalenone;6-hydroxy-3,4-dihydronaphthalen-2(1H)-one;3,4-Dihydro-6-hydroxynaphthalen-2(1H)-one;6-Hydroxy-2-tetralone, 6-Hydroxy-2-oxo-1,2,3,4-tetrahydronaphthalene
• CAS NO: 52727-28-3
• Molecular Formula: C₁₀H₁₀O₂
• Molecular Weight: 162.19
• Mol File: 52727-28-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 353.3 °C at 760 mmHg
• Flash Point: 150.6 °C
• Appearance: /
• Density: 1.236 g/cm³
• Vapor Pressure: 1.77E-05mmHg at 25°C
• Refractive Index: 1.602
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• PKA: 9.88±0.20(Predicted)
• CAS DataBase Reference: 6-Hydroxyl-2-tetralone(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Hydroxyl-2-tetralone(52727-28-3)
• EPA Substance Registry System: 6-Hydroxyl-2-tetralone(52727-28-3)

Safety Data

• Hazardous Substances Data: 52727-28-3(Hazardous Substances Data)

Usage

Physical Form

solid

InChI:InChI=1/C10H10O2/c11-9-3-1-7-5-10(12)4-2-8(7)6-9/h1,3,6,11H,2,4-5H2

Upstream product

• 74-85-1 ethene 
• 37859-23-7 2-(p-hydroxyphenyl)acetyl chloride 
• 2472-22-2 6-methoxy-2-tetralone 
• 530-93-8 1,2,3,4-tetrahydronaphthalen-2-one 
• 581-43-1 2.6-dihydroxynaphthalene 

Relevant articles and documents

Tetrahydroxynaphthalene reductase: Catalytic properties of an enzyme involved in reductive asymmetric naphthol dearomatization

In reduced circumstances: Tetrahydroxynaphthalene reductase shows a broad substrate range including alternate phenolic compounds and cyclic ketones. Structural modeling reveals major enzyme-substrate interactions; C-terminal truncation of the enzyme causes an altered substrate preference, in accordance with stabilization of the substrate by the C-terminal carboxylate (see picture). This effect allows the identification of a homologous enzyme. Copyright

Ionic hydrogenation of dihydroxynaphthalenes with cyclohexane in the presence of aluminum bromide

Reactions of 1,5-, 1,6-, 1,7-, 2,6-, and 2,7-dihydroxynaphthalenes with cyclohexane in the presence of excess aluminum bromide in methylene bromide quantitatively yield 5-, 6-, and 7-hydroxynaphthalen-1-ones and 6- and 7-hydroxynaphthalen-2-ones, respectively. Tricationic C-protonated complexes are presumed to be reactive intermediates in these processes.

HYDROXYLATION DU BENZALDEHYDE ET DE CETONES AROMATIQUES PAR LE PEROXYDE D'HYDROGENE EN MILIEU SUPERACIDE

Benzaldehyde and aromatic ketones are hydroxylated by hydrogen peroxide in SbF5-HF without formation of products arising from Baeyer-Villiger oxidation.