34743-87-8 Usage
Description
2-Phenoxyethyl chloroformate is a chemical compound characterized by the molecular formula C9H9ClO3. It is a clear, colorless liquid that serves as a reagent in organic synthesis, specifically for the introduction of the phenoxyethyl chloroformate functional group into a variety of organic compounds. This versatile compound is widely utilized in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals, and also functions as a protecting group for alcohols in organic synthesis. However, it is recognized for its potential to cause irritation to the skin, eyes, and respiratory system, necessitating careful handling in well-ventilated areas with appropriate personal protective equipment.
Uses
Used in Pharmaceutical Synthesis:
2-Phenoxyethyl chloroformate is used as a reagent in the pharmaceutical industry for the synthesis of various drugs. Its ability to introduce the phenoxyethyl chloroformate functional group into organic compounds aids in the creation of new pharmaceutical agents with specific therapeutic properties.
Used in Agrochemical Production:
In the agrochemical sector, 2-Phenoxyethyl chloroformate is employed as a reagent in the synthesis of agrochemicals. Its role in introducing the phenoxyethyl chloroformate group into organic compounds contributes to the development of effective crop protection products and other agricultural chemicals.
Used as a Protecting Group in Organic Synthesis:
2-Phenoxyethyl chloroformate is utilized as a protecting group for alcohols in organic synthesis. This application is crucial for preventing unwanted reactions from occurring at the alcohol functional group during complex organic synthesis processes, thereby ensuring the desired product is obtained.
Used in Fine Chemicals Synthesis:
2-Phenoxyethyl chloroformate is also used in the synthesis of fine chemicals, where the introduction of the phenoxyethyl chloroformate group can enhance the properties of the final product, such as solubility, stability, or reactivity, depending on the specific application.
Safety Considerations:
Given its potential to cause irritation, 2-Phenoxyethyl chloroformate should be handled with care, using proper personal protective equipment and ensuring that the work area is well-ventilated to minimize health risks to those involved in its use and production.
Check Digit Verification of cas no
The CAS Registry Mumber 34743-87-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,4,7,4 and 3 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 34743-87:
(7*3)+(6*4)+(5*7)+(4*4)+(3*3)+(2*8)+(1*7)=128
128 % 10 = 8
So 34743-87-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H9ClO3/c10-9(11)13-7-6-12-8-4-2-1-3-5-8/h1-5H,6-7H2
34743-87-8Relevant articles and documents
Beta lactam compounds and their use as inhibitors of tryptase
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Page column 276, (2010/11/29)
Compounds of the formulas: are disclosed. These compounds inhibit tryptase as well as other enzyme systems or are selective tryptase inhibitors and are useful as antiinflammatory agents particularly in the treatment of chronic asthma.
1-Aziridine carboxylic acid derivatives with immunostimulant activity
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, (2008/06/13)
2-Substituted-1-aziridine-carboxylic acid esters exhibiting immuno-stimulant activity and of the formula STR1 wherein X is a carbamoyl or alkoxycarbonyl radical, and R1 is an aliphatic hydrocarbon radical optionally substituted by halogen, alkoxy, amino, carbamoyloxy, cycloalkyl, hydroxyl, an imido or heterocyclic radical, cycloalkyl; or aryl, aralkyl, aryloxyalkyl or arylthioalkyl wherein the aryl moiety is optionally substituted by halogen, alkyl, alkoxy, hydroxyl, amino, nitro, cyano, acyl, carbalkoxy, thioalkyl, alkylsulphonyl, phenyl or trifluoromethyl. Counterparts where X is --CN and R1 is as above, except for ethyl, are also new.
