321166-01-2Relevant articles and documents
Inversion of the direction of stereoinduction in the coupling of chiral γ,δ-unsaturated fischer carbene complexes with o-ethynylbenzaldehyde
Ghorai, Binay K.,Menon, Suneetha,Lee Johnson, Dennis,Herndon, James W.
, p. 2121 - 2124 (2007/10/03)
(matrix presented) A variety of γ,δ-unsaturated carbene complexes that feature a stereogenic center at the β-carbon couple with 2-ethynylbenzaldehyde to afford hydrophenanthrene derivatives with a high degree of stereoinduction. The direction of stereoinduction is opposite for examples where the stereogenic center is acyclic vs examples where it is within a ring.