2915-90-4

Basic information

• Product Name: N,N-DIDODECYLMETHYLAMINE
• Synonyms: N,N-DIDODECYLMETHYLAMINE;N-METHYLDIDODECYLAMINE;N-Dodecyl-N-methyl-1-dodecanamine;dilauryl(methyl)amine;N-dodecyl-N-methyl-dodecan-1-amine;N-dodecyl-N-methyldodecan-1-amine;Didodecyl methyl amine;N,N-Didodecylmethylamine
• CAS NO: 2915-90-4
• Molecular Formula: C₂₅H₅₃N
• Molecular Weight: 367.7
• EINECS: 220-838-2
• Mol File: 2915-90-4.mol
• Article Data: 21

Chemical Properties

• Melting Point: 16 °C
• Boiling Point: 204 °C / 2mmHg
• Flash Point: 194.2°C
• Appearance: /
• Density: 0.82
• Vapor Pressure: 6.34E-08mmHg at 25°C
• Refractive Index: 1.4500-1.4540
• PKA: 9.81±0.50(Predicted)
• CAS DataBase Reference: N,N-DIDODECYLMETHYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-DIDODECYLMETHYLAMINE(2915-90-4)
• EPA Substance Registry System: N,N-DIDODECYLMETHYLAMINE(2915-90-4)

Safety Data

• Hazardous Substances Data: 2915-90-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
N,N-DIDODECYLMETHYLAMINE is used as a starting material for the preparation of emodin quaternary ammonium salt derivatives, which possess antitumor activity. These derivatives have potential applications in the development of novel anticancer drugs, targeting various types of cancer cells and contributing to the advancement of cancer treatment.
Used in Cosmetics Industry:
N,N-DIDODECYLMETHYLAMINE is used as an ingredient in the formulation of cosmetics, particularly in creams and lotions, due to its emulsifying and surfactant properties. It helps in stabilizing the formulation and improving the texture and consistency of the products, making them more appealing and effective for skin care applications.
Used in Textile Industry:
In the textile industry, N,N-DIDODECYLMETHYLAMINE is used as a softening agent and antistatic agent. Its cationic nature allows it to interact with the negatively charged textile fibers, providing a soft and smooth feel to the fabrics and reducing static electricity build-up.
Used in Detergent and Cleaning Industry:
N,N-DIDODECYLMETHYLAMINE is used as a component in the formulation of detergents and cleaning agents. Its surfactant properties enable it to lower the surface tension of water, facilitating the removal of dirt and stains from various surfaces. Additionally, its cationic nature makes it effective in softening fabrics and preventing the re-deposition of dirt during the washing process.
Used in Oil and Gas Industry:
In the oil and gas industry, N,N-DIDODECYLMETHYLAMINE is used as a corrosion inhibitor and as a component in the formulation of drilling muds. Its amphiphilic properties help in reducing the corrosion rate of metal surfaces in contact with water and other corrosive agents, while also improving the rheological properties of drilling muds for efficient drilling operations.

InChI:InChI=1/C25H53N/c1-4-6-8-10-12-14-16-18-20-22-24-26(3)25-23-21-19-17-15-13-11-9-7-5-2/h4-25H2,1-3H3

Upstream product

• 7311-30-0 N-methyldodecylamine 
• 112-52-7 1-chlorododecane 
• 74-89-5 methylamine 
• 67-56-1 methanol 
• 2437-25-4 undecyl cyanide 
• 50-00-0 formaldehyd 
• 3007-31-6 N,N-didodecylamine 
• 64-18-6 formic acid 
• 124-22-1 n-Dodecylamine 
• 112-18-5 N,N-dimethylaminododecane 
• 143-15-7 1-dodecylbromide 
• 3007-53-2 N,N-dimethyldodecanamide 
• 111-82-0 methyl n-dodecanoate 
• 112-53-8 1-dodecyl alcohol 

Downstream Products

• 3401-74-9 N,N-dimethyl-N,N-didodecylammonium chloride 
• 3282-73-3 N,N-didodecyl-N,N-dimethylammonium bromide 

Relevant articles and documents

Structurally related glucosylated liposomes: Correlation of physicochemical and biological features

Liposomes functionalized on their surface with carbohydrates (glycoliposomes) represent an optimal approach for targeting of drugs to diseased tissues in vivo, thanks to biocompatibility, low toxicity and easy manufacturing of these lipid nanoparticles. Here we report on the study of liposomes including a novel glycosylated amphiphile and on the comparison of their features with those of glycosylated analogues described previously. Further, the capability of the different glucosylated formulations to interact with three breast cancer cell lines was investigated. Our results show that the hydrophobic portion of the lipid bilayer strongly influences both the properties and the internalization of glycosylated liposomes.

Surface-active properties of novel cationic surfactants with two alkyl chains and two ammonio groups

A series of bis-quaternary ammonium salts was easily prepared by the reaction of a long-chain tert-alkylamine with epichlorohydrin, and their surface-active properties were measured. The prepared amphipathic compounds had good water solubility and showed characteristic surface-active properties, particularly, extremely excellent foaming ability and foam stability for some specific compounds, such as the compound with a dodecyl and a tetradecyl group as the lipophilic chains. Their critical micelle concentration, which decreased with increased alkyl chainlength, is two orders of magnitude lower compared with the conventional mono-quaternary ammonium salts. In comparison with surface-active properties of bis-quaternary ammonium salts, prepared from various organic dichlorides, there are little differences based on the kind of connecting group in the surface-active properties except for foaming. Copyright

Diverse catalytic reactivity of a dearomatized PN3P?-nickel hydride pincer complex towards CO2 reduction

A dearomatized PN3P?-nickel hydride complex has been prepared using an oxidative addition process. The first nickel-catalyzed hydrosilylation of CO2 to methanol has been achieved, with unprecedented turnover numbers. Selective methylation and formylation of amines with CO2 were demonstrated by such a PN3P?-nickel hydride complex, highlighting its versatile functions in CO2 reduction.

METHOD FOR PRODUCING TERTIARY AMINE

The present invention provides a method for producing a tertiary amine by using a secondary amine and an alcohol as starting materials to obtain a corresponding tertiary amine. The method of the present invention includes reacting a secondary amine with an alcohol in the presence of a catalyst, wherein the catalyst is previously used in the reaction of a primary amine with an alcohol to obtain a tertiary amine.

PROCESS FOR PRODUCING NITROGEN-CONTAINING COMPOUNDS

The present invention relates to a process for producing a tertiary amine by reducing an amide compound in the presence of a catalyst containing a sponge copper catalyst obtained by leaching alloy particles containing copper and aluminum and drying the thus leached alloy particles. The present invention provides a process for producing high-purity aliphatic tertiary amines containing a less amount of by-products at a high yield by subjecting aliphatic acid amides to hydrogenation reduction under solvent-free moderate conditions.

METHOD FOR PRODUCING TERTIARY AMINE

The present invention provides a method for producing a tertiary amine by reacting an alcohol with a primary or secondary amine in the presence of a film catalyst containing a thermosetting resin and an active metal, wherein the film catalyst is reduced at 100 to 150° C., and a method for activating the film catalyst containing a thermosetting resin and an active metal, including applying a coating agent containing the thermosetting resin and a powder catalyst onto the surface of a support, drying the resultant, curing it at 80 to 170° C., and reducing the catalyst at 100 to 150° C.

METHOD OF PRODUCING NITROGEN-CONTAINING COMPOUND

The present invention provides a process for producing high-purity aliphatic tertiary amines containing a less amount of by-products by using a chromium-free catalyst with a good productivity in an economically advantageous manner. The present invention relates to a process for producing a tertiary amine by reducing an amide compound in the presence of a catalyst containing copper and magnesium at a molar ratio of magnesium to copper (magnesium/copper) of from 0.01 to 20.

PROCESS FOR PRODUCING NITROGEN-CONTAINING COMPOUNDS

The present invention relates to a process for producing a tertiary amine in the presence of a catalyst containing copper and at least one element selected from the group consisting of elements belonging to Groups 2, 3, 7 and 12 of the Periodic Table (long form of the periodic table), said process including the steps of (a) reducing an amide compound in a hydrogen atmosphere; and (b) introducing a dialkyl amine containing a linear or branched alkyl group having 1 to 6 carbon atoms into a reaction product obtained in the step (a), and treating the reaction product with the dialkyl amine. The present invention provides a process for producing high-purity aliphatic tertiary amines containing a less amount of by-products by reducing aliphatic acid amides under moderate conditions using a chromium-free catalyst, as well as a process for producing amine derivatives such as amine oxide by using the aliphatic tertiary amines, with a good productivity in an economical manner.

Synthesis of novel 5'-uridine-head amphiphiles as model for DNA molecular recognition

Here we describe uridine functionalization in the 5' position, which provides new classes of cationic and nonionic amphiphiles specifically designed as DNA transfection agents. The synthetic procedures developed to obtain the cationic uridine-head surfactants prevented intramolecular cyclization that occurs when uridine is functionalized in this position without using protecting groups in the uracil.

METHOD FOR PRODUCING NITROGEN-CONTAINING COMPOUND

The present invention provides a process for producing high-purity aliphatic tertiary amines containing a less amount of by-products by subjecting aliphatic acid amides to hydrogenation reduction under moderate conditions, as well as a process for producing amine derivatives from the aliphatic tertiary amines, with a good productivity in an economically advantageous manner. The present invention relates to a process for producing an aliphatic tertiary amine by subjecting a specific aliphatic amide to hydrogenation reduction in the presence of a catalyst containing copper and at least one element selected from the group consisting of elements belonging to Groups 2, 3 and 7 of the Periodic Table; the catalyst; and a process for producing amine oxide by reacting the tertiary amide obtained by the above production process with hydrogen peroxide.