1-Dodecanamine, N-dodecyl-N-methyl-

Base Information

• Chemical Name: 1-Dodecanamine, N-dodecyl-N-methyl-
• CAS No.: 2915-90-4
• Molecular Formula: C25H53 N
• Molecular Weight: 367.703
• Hs Code.: 2921199090
• European Community (EC) Number: 220-838-2
• NSC Number: 30889
• UNII: 91F5U5022X
• DSSTox Substance ID: DTXSID6062707
• Nikkaji Number: J306.842K
• Wikidata: Q27271396
• Mol file: 2915-90-4.mol

Synonyms:2915-90-4;1-Dodecanamine, N-dodecyl-N-methyl-;N,N-Didodecylmethylamine;N-Methyldidodecylamine;N-dodecyl-N-methyldodecan-1-amine;dilaurylmethylamine;didodecylmethylamine;UNII-91F5U5022X;EINECS 220-838-2;NSC-30889;91F5U5022X;methyldidodecylamine;Didodecyl methyl amine;n-Dodecyl-N-methyl-1-dodecanamine;NSC30889;didodecyl methylamine;dilaurylmonomethylamine;n,n-didodecyl-n-methylamine;SCHEMBL111382;DTXSID6062707;FARMIN M 2-2095;C25H53N;DIDODECYLAMINE, N-METHYL-;N-METHYL-N,N-DIDODECYLAMINE;MFCD06252158;NSC 30889;n-Dodecyl-N-methyl-1-dodecanamine #;AKOS015914850;AS-75581;CS-0450517;D3338;FT-0658539;Q27271396

Chemical Property of 1-Dodecanamine, N-dodecyl-N-methyl-

Chemical Property:

• Vapor Pressure: 6.34E-08mmHg at 25°C
• Melting Point: 16 °C
• Refractive Index: 1.454
• Boiling Point: 204 °C / 2mmHg
• PKA: 9.81±0.50(Predicted)
• Flash Point: 194.2°C
• PSA: 3.24000
• Density: 0.819g/cm³
• LogP: 8.76000
• XLogP3: 11.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 22
• Exact Mass: 367.417800695
• Heavy Atom Count: 26
• Complexity: 214

Purity/Quality:

99% ^*data from raw suppliers

Didodecylmethylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCN(C)CCCCCCCCCCCC
• Uses: Didodecylmethylamine has been used in the preparation of emodin quaternary ammonium salt derivatives with antitumor activity.

Technology Process of 1-Dodecanamine, N-dodecyl-N-methyl-

There total 27 articles about 1-Dodecanamine, N-dodecyl-N-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

N,N-didodecylamine (3007-31-6) + carbon dioxide (124-38-9,18923-20-1) → N-methyldidodecylamine (2915-90-4)

Guidance literature:

With diphenylsilane; C₂₁H₄₁N₃NiP₂; In acetonitrile; at 120 ℃; for 24h; under 2052.14 Torr; Autoclave;

DOI:10.1039/c8cc05948a

Reference yield: 87.7%

1-dodecyl alcohol (112-53-8) + dimethyl amine (124-40-3) → N,N-dimethylaminododecane (112-18-5,83855-86-1) + N-methyldidodecylamine (2915-90-4)

Guidance literature:

With hydrogen; Cu, Ni, Ru film catalyst containing thermosetting resin; at 220 ℃; for 6.7h; Product distribution / selectivity;

Reference yield: 83.8%

N,N-dimethyldodecanamide (3007-53-2) → N,N-dimethylaminododecane (112-18-5,83855-86-1) + 1-dodecyl alcohol (112-53-8) + N-methyldidodecylamine (2915-90-4)

Guidance literature:

With hydrogen; magnesium/copper (0.76 ratio) oxide catalyst with copper content 40percent by mass; at 250 ℃; for 6h; under 11251.1 Torr; Product distribution / selectivity; Autoclave;

upstream raw materials:

formaldehyd

formic acid

N,N-didodecylamine

N-methyldodecylamine

Downstream raw materials:

N,N-dimethyl-N,N-didodecylammonium chloride

N,N-didodecyl-N,N-dimethylammonium bromide

Refernces

• 1、 Mauceri, Alessandro,Giansanti, Luisa,Bozzuto, Giuseppina,Condello, Maria,Molinari, Agnese,Galantini, Luciano,Piozzi, Antonella,Mancini, Giovanna. "Structurally related glucosylated liposomes: Correlation of physicochemical and biological features". . p. 1468 - 1475. Retrieved 2019.
• 2、 Li, Huaifeng,Gon?alves, Théo P.,Zhao, Qianyi,Gong, Dirong,Lai, Zhiping,Wang, Zhixiang,Zheng, Junrong,Huang, Kuo-Wei. "Diverse catalytic reactivity of a dearomatized PN3P?-nickel hydride pincer complex towards CO2 reduction". supporting information. p. 11395 - 11398. Retrieved 2018/10/20.
• 3、 -. "METHOD FOR PRODUCING TERTIARY AMINE". Page/Page column 5. . Retrieved 2010/09/05.