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280762-58-5

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280762-58-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 280762-58-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,0,7,6 and 2 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 280762-58:
(8*2)+(7*8)+(6*0)+(5*7)+(4*6)+(3*2)+(2*5)+(1*8)=155
155 % 10 = 5
So 280762-58-5 is a valid CAS Registry Number.

280762-58-5Relevant articles and documents

PICOLINIC ACID DERIVATIVES AND USE THEREOF FOR TREATING DISEASES ASSOCIATED WITH ELEVATED CHOLESTEROL

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, (2020/12/11)

Formula I The present invention relates to compounds of Formula (I), wherein X is as defined above; Y is OR3; Z is H, optionally substituted alkyl or - CH2OR4; L is optionally substituted alkyl or heteroalkyl; R1 is H, -OH, optionally substituted alkyl, heterocycle, aryl or heteroaryl; R2 is NR5R6, or OR5; each of R3 and R4 is H or optionally substituted alkyl, benzyl, phenyl or heterocycle; or R3 and R4 combine to form an optionally substituted heterocycle; R5 is H or optionally substituted alkyl, cycloalkyl, heteroalkyl, alkylaryl or heterocycle; and R6 is H or alkyl, or pharmaceutically acceptable salts, solvates or compositions thereof. Compounds of formula (I) significantly increase low density lipoprotein receptor expression and activity, lower total circulating cholesterol and are useful for treating and delaying the onset of diseases associated with elevated cholesterol, such as atherosclerosis and hypercholesterolemia.

HIV INTEGRASE INHIBITORS FROM PYRIDOXINE

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Page/Page column 57, (2009/12/28)

The present invention relates to pyridoxine (vitamin B6) derived compounds of formula (I), pharmaceutically acceptable salts, or solvates thereof, wherein R1, R2, R4, A, L B1 and B2 are as defined in the specification, and pharmaceutical compositions comprising the compounds. Compounds of formula (I) inhibit Human Immunodeficiency Virus (HΙV)-integrase enzyme and are useful for preventing and treating HIV infection and AIDS.

Versatile synthesis of (+)-deoxypyridinoline, a biochemical marker for diagnosis of osteoporosis

Adamczyk, Maciej,Rao Akireddy, Srinivasa,Reddy, Rajarathnam E.

, p. 3107 - 3110 (2007/10/03)

A versatile chiral synthesis of the bone collagen cross-link, (+)-deoxypyridinoline (Dpd, 1) was described starting from a 3-hydroxypyridine derivative (2) via sequential introduction of three amino acid chains followed by hydrolysis. The key synthon 2, was prepared from vitamin B6 (6).

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