2802-62-2

Basic information

• Product Name: 4,6-DIFLUOROPYRIMIDINE
• Synonyms: 4,6-DIFLUOROPYRIMIDINE;Pyrimidine, 4,6-difluoro- (6CI,8CI,9CI);PyriMidine,4,6-difluoro-
• CAS NO: 2802-62-2
• Molecular Formula: C₄H₂F₂N₂
• Molecular Weight: 116.07
• Product Categories: PYRIMIDINE;Pyridines, Pyrimidines, Purines and Pteredines
• Mol File: 2802-62-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 125℃
• Flash Point: 29℃
• Appearance: /
• Density: 1.376
• Vapor Pressure: 15.2mmHg at 25°C
• Refractive Index: 1.444
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -4.88±0.17(Predicted)
• CAS DataBase Reference: 4,6-DIFLUOROPYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-DIFLUOROPYRIMIDINE(2802-62-2)
• EPA Substance Registry System: 4,6-DIFLUOROPYRIMIDINE(2802-62-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-41
• Safety Statements: 26-36/37/39-39
• HazardClass: IRRITANT
• Hazardous Substances Data: 2802-62-2(Hazardous Substances Data)

Usage

Description

4,6-difluoropyrimidine is a chemical compound with the molecular formula C4H2F2N2, belonging to the pyrimidine group of organic compounds. It is characterized by the presence of two fluorine atoms on the 4th and 6th positions of the pyrimidine ring structure, which endows it with unique properties and reactivity.

Uses

Used in Pharmaceutical Industry:
4,6-difluoropyrimidine is used as a building block for the synthesis of various biologically active compounds due to its unique structure and reactivity. It plays a crucial role in the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 4,6-difluoropyrimidine is utilized as a key intermediate in the synthesis of agrochemicals, contributing to the development of effective pesticides and other agricultural chemicals.
Used in Material Science:
4,6-difluoropyrimidine may have applications in the field of material science, where its unique properties can be harnessed to create novel materials with specific characteristics for various applications.
Used as a Reagent in Organic Chemistry Reactions:
Due to its reactivity, 4,6-difluoropyrimidine serves as an important reagent in various organic chemistry reactions, facilitating the synthesis of a wide range of valuable substances.

InChI:InChI=1/C4H2F2N2/c5-3-1-4(6)8-2-7-3/h1-2H

Upstream product

• 1193-21-1 4,6-dichloropyrimidine 

Downstream Products

• 289-95-2 PYRIMIDINE 
• 196809-90-2 4-fluoro-6-[(α,α,α-trifluoro-m-tolyl)oxy]pyrimidine 
• 862270-56-2 4-fluoro-6-(4-(1-(4-fluorophenyl)ethyl)piperazin-1-yl)pyrimidine 

Relevant articles and documents

DIARYL UREA DERIVATIVES USEFUL FOR THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES

The invention relates to the use of diaryl urea derivatives in the treatment of protein kinase dependent diseases or for the manufacture of pharmaceutical compositions for use in the treatment of said diseases, methods of use of diaryl urea derivatives in the treatment of said diseases, pharmaceutical preparations comprising diaryl urea derivatives for the treatment of said diseases, diaryl urea derivatives for use in the treatment of said diseases, novel diaryl urea derivatives, pharmaceutical preparations comprising these novel diaryl urea derivatives, processes for the manufacture of the novel diaryl urea derivatives, the use or methods of use of the novel diaryl urea derivatives as mentioned above, and/or these novel diaryl urea derivatives for use in the treatment of the animal or human body.

Process for the preparation of unsymmertical 4,6-Bis (aryloxy pyrimidine compounds

There is provided a process for the preparation of unsymmetrical 4,6-bis(aryloxy)pyrimidine compounds. The unsymmetrical 4,6-bis(aryloxy)pyrimidine compounds are useful as pesticidal agents.

Fungicides

Compounds having the formula (I): STR1 in which any two of K, L and M are nitrogen and the other is CE; X and Y are independently hydrogen, halogen, C1-4 alkyl, C3-6 cycloalkyl, C2-4 alkenyl, C2-4 alkynyl, C2-4 alkynyloxy, phenyl, benzyloxy, cyano, isocyano, isothiocyanato, nitro, NR1 R2, NR1 OR2, N3, NHCOR1, NR1 CO2 R2, NHCONR1 R2, N=CHNR1 R2, NHSO2 R1, OR1, OCOR1, OSO2 R1, SR1, SOR1, SO2 R1, SO2 OR1, SO2 NR1 R2, COR1, CR1 =NOR2, CHR1 CO2 R2, CO2 R1, CONR1 R2, CSNR1 R2, CH3 O2 C.C:CH.OCH3, 1-(imidazol-1-yl)vinyl, a 5-membered heterocyclic ring containing one, two or three nitrogen heteroatoms, or a 5- or 6-membered heterocyclic ring containing one or two oxygen or sulphur hetero-atoms, optionally a nitrogen heteroatom and optionally one or two oxo or thioxo substituents; or X and Y, when ortho to one another, join to form a 5- or 6-membered aliphatic or aromatic ring optionally containing one or two oxygen, sulphur or nitrogen atoms or one, two or three nitrogen atoms; A, B, D, E, G, U and V are independently hydrogen, halogen, C1-4 alkyl C1-4 alkoxy, cyano, nitro or trifluoromethyl; and R1 and R2 are independently hydrogen, C1-4 alkyl, C2-4 alkenyl or phenyl; the aliphatic moieties of any of the foregoing being optionally substituted with one or more of halogen, cyano, OR1, SR1, NR1 R2, SiR13 or OCOR1 and the phenyl moieties of any of the foregoing being optionally substituted with one or more of halogen, C1-4 alkyl, C1-4 alkoxy, nitro or cyano. The compounds are useful as fungicides.