273408-90-5

Basic information

• Product Name: 2-PYRIDIN-3-YL-QUINAZOLIN-4-YLAMINE
• Synonyms: 2-(PYRIDIN-3-YL)QUINAZOLIN-4-AMINE;2-PYRIDIN-3-YL-QUINAZOLIN-4-YLAMINE;BUTTPARK 63\09-50;Pyridinylquinazolinylamine 234------
• CAS NO: 273408-90-5
• Molecular Formula: C₁₃H₁₀N₄
• Molecular Weight: 222.25
• Mol File: 273408-90-5.mol
• Article Data: 7

Chemical Properties

• Melting Point: 185-188 °C
• Boiling Point: 352.3°C at 760 mmHg
• Flash Point: 194°C
• Appearance: /
• Density: 1.301g/cm³
• Vapor Pressure: 3.87E-05mmHg at 25°C
• Refractive Index: 1.716
• Storage Temp.: 2-8°C
• PKA: 4.71±0.30(Predicted)
• CAS DataBase Reference: 2-PYRIDIN-3-YL-QUINAZOLIN-4-YLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-PYRIDIN-3-YL-QUINAZOLIN-4-YLAMINE(273408-90-5)
• EPA Substance Registry System: 2-PYRIDIN-3-YL-QUINAZOLIN-4-YLAMINE(273408-90-5)

Safety Data

• Hazard Codes: Xi,T
• Statements: 25
• Safety Statements: 45
• HazardClass: IRRITANT
• Hazardous Substances Data: 273408-90-5(Hazardous Substances Data)

Usage

General Description

2-Pyridin-3-yl-quinazolin-4-ylamine is a chemical compound that belongs to the class of quinazoline derivatives. It is a heterocyclic compound containing both pyridine and quinazoline rings. 2-PYRIDIN-3-YL-QUINAZOLIN-4-YLAMINE has potential applications in medicinal chemistry and drug discovery due to its ability to interact with biological systems. It may exhibit pharmacological activity, making it a potential candidate for the development of new drugs. Its structure and properties make it an interesting target for further research and exploration in the field of pharmaceuticals and biochemistry.

InChI:InChI=1/C13H10N4/c14-12-10-5-1-2-6-11(10)16-13(17-12)9-4-3-7-15-8-9/h1-8H,(H2,14,16,17)

Upstream product

• 59-67-6 nicotinic acid 
• 1885-29-6 anthranilic acid nitrile 
• 15432-24-3 2-(pyridin-3-yl)-indole 
• 4387-36-4 2-iodobenzonitrile 
• 500-22-1 3-pyridinecarboxaldehyde 
• 885953-16-2 2-iodobenzimidamide 
• 2042-37-7 o-cyanobromobenzene 
• 100-54-9 pyridine-3-carbonitrile 

Downstream Products

• 280570-45-8 VUF 5574 

Relevant articles and documents

RECEPTOR TYROSINE KINASE INHIBITORS FOR TREATMENT OF PROTEIN KINASE MODULATION-RESPONSIVE DISEASE OR DISORDER

Ephrin type receptor tyrosine kinase inhibitors, also known as Eph tyrosine kinase receptor inhibitors, for treating cancer, an inflammatory disease, an autoimmune disease, or a degenerative disease characterized at least in part by the abnormal activity

A Highly Efficient Copper-Catalyzed Three-Component Synthesis of 4-Aminoquinazolines

A highly efficient copper-catalyzed one-pot protocol is developed for the synthesis of 4-aminoquinazolines from easily available 2-iodo- or 2-bromobenzimidamides, aldehydes, and sodium azide. This one-pot approach proceeds via consecutive copper-catalyzed SNAr substitution, reduction, cyclization, oxidation and tautomerization. The corresponding target products (26 examples) are obtained in 50-90% yield.

An efficient method to prepare 4-aminoquinazolines: Potential application to conformation-restricted bleomycin analogs

(Chemical Equation Presented) To enhance the iron-chelating ability of P-3A, 4-aminoquinazolines were designed as conformation-restricted bleomycin analogs. An efficient method was developed to prepare the 4-aminoquinazoline heterocyclic nucleus, which en