25152-85-6Relevant articles and documents
Regioselective Wacker-Type Oxidation of Internal Olefins in tBuOH Using Oxygen as the Sole Oxidant and tBuONO as the Organic Redox Cocatalyst
Huang, Qing,Li, Ya-Wei,Ning, Xiao-Shan,Jiang, Guo-Qing,Zhang, Xiao-Wei,Qu, Jian-Ping,Kang, Yan-Biao
supporting information, p. 965 - 969 (2020/02/15)
A regioselective Wacker-Tsuji oxidation of internal olefins in tBuOH has been developed using oxygen as the terminal oxidant and tert-butyl nitrite as the simple organic redox cocatalyst without the involvement of hazardous cocatalysts or harsh reaction conditions. A series of internal olefins bearing various functional groups can be oxidized to the corresponding substituted ketones in generally good yields with high regioselectivities.
Benzoyl peroxide-imidazole: A novel and efficient reagent for the mild conversion of alcohols or phenols into benzoates
Nowrouzi, Najmeh,Alizadeh, Seyedeh Zahra
, p. 2412 - 2414 (2013/06/26)
A very mild, one-pot, and expedient protocol for the conversion of alcohols and phenols into their corresponding benzoates using imidazole and benzoyl peroxide as a novel reagent is described.
Wacker-type oxidation of internal alkenes using Pd(Quinox) and TBHP
Deluca, Ryan J.,Edwards, Jennifer L.,Steffens, Laura D.,Michel, Brian W.,Qiao, Xiaoxiao,Zhu, Chunyin,Cook, Silas P.,Sigman, Matthew S.
, p. 1682 - 1686 (2013/04/10)
The Pd-catalyzed TBHP-mediated Wacker-type oxidation of internal alkenes is reported. The reaction uses 2-(4,5-dihydro-2-oxazolyl)quinoline (Quinox) as ligand and TBHP(aq) as oxidant to deliver single ketone constitutional isomer products in a predictable fashion from electronically biased olefins. This methodology is showcased through its application on an advanced intermediate in the total synthesis of the antimalarial drug artemisinin.
Consequences of Affinity in Heterogeneous Catalytic Reactions: Highly Chemoselective Hydrogenolysis of Iodoarenes
Ambroise, Yves,Mioskowski, Charles,Djega-Mariadassou, Gerald,Rousseau, Bernard
, p. 7183 - 7186 (2007/10/03)
The catalytic hydrodeiodination reaction using molecular hydrogen and Pd/C has been revisited. It is shown, for the first time, that the chemoselectivity of this reaction is controlled by the high affinity of the iodinated compound for the catalyst. This reaction is compatible with most easily reducible functional groups (nitro, aldehyde, olefin, etc.). Using this reaction, the first general method for tritium labeling of 3-(trifluoromethyl)-3-phenyldiazirine is described.