220141-74-2 Usage
Description
2,4,5-Trifluorophenylacetonitrile is a synthetic chemical compound that belongs to the group of organic compounds known as nitriles. It is characterized by the presence of fluorine atoms and a cyano group (-CN) in its structure, which imparts unique chemical properties. With the chemical formula C8H3F3N, this compound is often utilized in pharmaceutical research and development for its potential to create distinctive molecular structures. It is typically found as a clear colorless liquid and is known for its potent, often unpleasant, odor. While it is valuable in research applications, it is important to handle 2,4,5-Trifluorophenylacetonitrile with care due to its potential health risks, such as eye and skin irritation and harm if ingested or inhaled.
Uses
Used in Pharmaceutical Research and Development:
2,4,5-Trifluorophenylacetonitrile is used as a key intermediate in the synthesis of various pharmaceutical compounds, particularly for creating unique molecular structures that can be further developed into potential drug candidates. Its presence in the molecular structure can influence the properties and efficacy of the resulting compounds, making it a valuable asset in the drug discovery process.
Used in Chemical Synthesis:
In the chemical industry, 2,4,5-Trifluorophenylacetonitrile is used as a building block for the synthesis of a wide range of organic compounds. Its reactivity and the presence of fluorine atoms make it a versatile starting material for the production of various specialty chemicals, including agrochemicals, dyes, and other industrial chemicals.
Used in Material Science:
2,4,5-Trifluorophenylacetonitrile is also employed in the development of new materials with specific properties, such as high thermal stability or unique electronic characteristics. Its incorporation into the molecular structure of these materials can lead to the creation of advanced materials with potential applications in various industries, including electronics, aerospace, and automotive.
Check Digit Verification of cas no
The CAS Registry Mumber 220141-74-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,0,1,4 and 1 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 220141-74:
(8*2)+(7*2)+(6*0)+(5*1)+(4*4)+(3*1)+(2*7)+(1*4)=72
72 % 10 = 2
So 220141-74-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H4F3N/c9-6-4-8(11)7(10)3-5(6)1-2-12/h3-4H,1H2
220141-74-2Relevant articles and documents
Preparation method of 2,4,5-trifluorophenylacetic acid
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, (2021/05/29)
The invention belongs to the technical field of preparation of drug intermediates, and discloses a preparation method of 2,4,5-trifluorophenylacetic acid, wherein the preparation method comprises the steps: step 1, reacting raw materials, a quaternary ammonium salt catalyst, sulfolane and potassium fluoride to obtain a first intermediate; step 2, carrying out hydrogenation catalytic reaction on the first intermediate to obtain a second intermediate; step 3, carrying out salt forming reaction on the second intermediate and a fluorinating reagent, quenching, and carrying out diazotization reaction on the second intermediate and a sodium nitrite aqueous solution to obtain diazonium salt; step 4, carrying out high-temperature cracking on the diazonium salt, to obtain 2,4,5-trifluorotoluene; and step 5 to step 7, carrying out halogenation, cyanidation and hydrolysis reactions on 2,4,5-trifluorotoluene in sequence, and thus obtaining 2,4,5-trifluorophenylacetic acid. The raw materials adopted by the method are easy to obtain and low in cost, the yield of the corresponding product obtained in each step is high, and large-scale production of the 2,4,5-trifluorophenylacetic acid is facilitated.