2041-37-4

Basic information

• Product Name: 2',2,2-TRIMETHYLPROPIOPHENONE
• Synonyms: 2',2,2-TRIMETHYLPROPIOPHENONE;2,2-DIMETHYL-1-(2-METHYLPHENYL)PROPAN-1-ONE
• CAS NO: 2041-37-4
• Molecular Formula: C₁₂H₁₆O
• Molecular Weight: 176.25
• Mol File: 2041-37-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 249.3°C at 760 mmHg
• Flash Point: 97.2°C
• Appearance: /
• Density: 0.943g/cm³
• Vapor Pressure: 0.0231mmHg at 25°C
• Refractive Index: 1.5
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2',2,2-TRIMETHYLPROPIOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2',2,2-TRIMETHYLPROPIOPHENONE(2041-37-4)
• EPA Substance Registry System: 2',2,2-TRIMETHYLPROPIOPHENONE(2041-37-4)

Safety Data

• Hazardous Substances Data: 2041-37-4(Hazardous Substances Data)

Usage

General Description

2',2,2-Trimethylpropiophenone, also known as TMP, is a chemical compound with the molecular formula C12H16O. It is commonly used as a flavor and fragrance ingredient, as well as an intermediate in the synthesis of pharmaceuticals and other organic compounds. TMP is a clear, colorless liquid with a characteristic sweet, floral odor, and is soluble in most organic solvents. It is used as a flavoring agent in the food industry and as a fragrance ingredient in the perfume industry. Additionally, it is utilized in the production of insecticides, pharmaceuticals, and other specialty chemicals. Its versatile properties make it a valuable compound in various industrial applications.

InChI:InChI=1/C12H16O/c1-9-7-5-6-8-10(9)11(13)12(2,3)4/h5-8H,1-4H3

Upstream product

• 55678-42-7 α-tert-butyl-2-methylbenzyl alcohol 
• 938-16-9 2,2-dimethylpropiophenone 
• 75-24-1 trimethylaluminum 
• 95-46-5 2-methylphenyl bromide 
• 3282-30-2 pivaloyl chloride 
• 815-24-7 Di-t-butyl ketone 
• 529-19-1 2-Methylbenzonitrile 
• 630-19-3 pivalaldehyde 
• 22526-24-5 1-(2-methoxyphenyl)-2,2-dimethyl-1-propanone 
• 66423-62-9 2,5,5-trimethyl-1,3,2-dioxaborinane 
• 108-88-3 toluene 
• 2259-30-5 tert-butylmagnesium bromide 
• 63162-57-2 2,2,4,4-tetramethyl-3-(2-methylphenyl)pentan-3-ol 
• 79722-72-8 2-<<2,2-dimethyl-1-(2-methylphenyl)propylidene>-amine>-2,4,4,-trimethylpentane 

Downstream Products

• 2674-45-5 3,3-diphenylisochroman-1-one 
• 95217-41-7 3-(4-methylphenyl)-3,4-dihydro-1H-isochromen-1-one 
• 27561-42-8 1-(3,3-dimethylbut-1-en-2-yl)-2-methylbenzene 
• 27561-43-9 3,3-Dimethyl-2-o-tolyl-1-aminobutan 
• 162052-57-5 tert-butyl 2-(trimethylsilyl)phenyl ketone 
• 55678-42-7 α-tert-butyl-2-methylbenzyl alcohol 
• 63162-57-2 2,2,4,4-tetramethyl-3-(2-methylphenyl)pentan-3-ol 
• 147394-42-1 1-(2-Ethylphenyl)-2,2-dimethylpropan-1-one 
• 147394-34-1 1-tert-Butyl-3-styryl-3,4-dihydro-1H-2-benzopyran-1-ol 
• 147394-32-9 1-tert-Butyl-3-(p-tolyl)-3,4-dihydro-1H-2-benzopyran-1-ol 
• 154502-68-8 ethyl 2-<2-(2,2-dimethylpropanoyl)phenyl>acetate 
• 147394-40-9 1-tert-Butyl-3,3-diphenyl-3,4-dihydro-1H-2-benzopyran-1-ol 
• 27561-36-0 2,2-dimethyl-1-o-tolylpropan-1-amine 
• 24785-42-0 1-(2,2-Dimethylpropyl)-2-methylbenzene 

Relevant articles and documents

Ruthenium-Catalyzed Functionalization of Aryl Carbon-Oxygen Bonds in Aromatic Ethers with Organoboron Compounds

The ruthenium-catalyzed reaction of aryl ethers having a carbonyl group at the ortho position to the ether group with organoboronates (R?B(OCH2CMe2CH2O), R = aryl, alkenyl, and alkyl) resulted in site-selective C?C bond formation. Among the transition metal complexes screened, the RuH2(CO)(PPh3)3 complex showed the highest activity. Several aromatic ketones having methoxy or phenoxy groups at the ortho position can also be used in this coupling reaction. A variety of arylboronates containing electron-donating (NMe2, OMe, methyl, and vinyl) and -withdrawing (F and CF3) groups reacted with methoxy ketones to give the corresponding coupling products in high yields. Copyright

Oxidative kinetic resolution of racemic alkyl aryl carbinols by an electronically tuned chiral nitroxyl radical

A method for oxidative kinetic resolution of racemic alcohols catalyzed by chiral nitroxyl radical (R,R)-1 has been developed. This method is especially effective for the kinetic resolution of tert-butyl aryl carbinols (s = up to 23).

Facile synthesis of pivalophenones by an ultrasound assisted iodine catalysed Friedel-Crafts acylation reaction

The use of ultrasound in the acylation reactions of various aromatics and heterocyclics with pivaloyl chloride in the presence of catalytic amount of iodine, without any added solvent and at room temperature, gives excellent yields of the respective pivalophenones in a short reaction time.