938-16-9 Usage
Description
2,2-DIMETHYLPROPIOPHENONE, also known as 2,2-dimethyl-1-phenyl-1-propanone, is an organic compound that has been synthesized through the electrocarboxylation process in N-methyl-2-pyrrolidone using a carbon cathode and an aluminium sacrificial anode. 2,2-DIMETHYLPROPIOPHENONE is characterized by its unique structure and properties, making it a potential candidate for various applications across different industries.
Uses
Used in Chemical Synthesis Industry:
2,2-DIMETHYLPROPIOPHENONE is used as a key intermediate in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and specialty chemicals. Its unique structure allows for versatile chemical reactions, making it a valuable building block in the development of new molecules with desired properties.
Used in Pharmaceutical Industry:
2,2-DIMETHYLPROPIOPHENONE is used as a starting material for the synthesis of various pharmaceutical compounds, particularly those with potential therapeutic applications. Its unique structure and reactivity enable the development of new drugs with improved efficacy and safety profiles.
Used in Material Science:
2,2-DIMETHYLPROPIOPHENONE is used in the development of novel materials with specific properties, such as polymers, coatings, and adhesives. Its unique structure and reactivity contribute to the creation of materials with enhanced performance characteristics, such as improved durability, stability, and functionality.
Used in Research and Development:
2,2-DIMETHYLPROPIOPHENONE is used as a research compound in academic and industrial laboratories to explore its chemical properties, reactivity, and potential applications. Its unique structure and synthesis method provide valuable insights into the development of new synthetic routes and the discovery of new compounds with diverse applications.
Synthesis Reference(s)
Tetrahedron, 39, p. 3207, 1983 DOI: 10.1016/S0040-4020(01)91568-6Tetrahedron Letters, 37, p. 5381, 1996 DOI: 10.1016/0040-4039(96)01083-0Synthesis, p. 662, 1974 DOI: 10.1055/s-1974-23397
Check Digit Verification of cas no
The CAS Registry Mumber 938-16-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 9,3 and 8 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 938-16:
(5*9)+(4*3)+(3*8)+(2*1)+(1*6)=89
89 % 10 = 9
So 938-16-9 is a valid CAS Registry Number.
InChI:InChI=1/C11H14O/c1-11(2,3)10(12)9-7-5-4-6-8-9/h4-8H,1-3H3
938-16-9Relevant articles and documents
Maurer,Bargon
, p. 6865,6867 (1979)
Ruthenium-on-Carbon-Catalyzed Facile Solvent-Free Oxidation of Alcohols: Efficient Progress under Solid-Solid (Liquid)-Gas Conditions
Park, Kwihwan,Jiang, Jing,Yamada, Tsuyoshi,Sajiki, Hironao
, p. 1200 - 1205 (2021/12/29)
A protocol for the ruthenium-on-carbon (Ru/C)-catalyzed solvent-free oxidation of alcohols, which proceeds efficiently under solid-solid (liquid)-gas conditions, was developed. Various primary and secondary alcohols were transformed to corresponding aldehydes and ketones in moderate to excellent isolated yields by simply stirring in the presence of 10% Ru/C under air or oxygen conditions. The solvent-free oxidation reactions proceeded efficiently regardless of the solid or liquid state of the substrates and reagents and could be applied to gram-scale synthesis without loss of the reaction efficiency. Furthermore, the catalytic activity of Ru/C was maintained after five reuse cycles.
Rhodium-Catalyzed and Chiral Zinc Carboxylate-Assisted Allenylation of Benzamides via Kinetic Resolution
Mao, Ruxia,Zhao, Yanliang,Zhu, Xiaohan,Wang, Fen,Deng, Wei-Qiao,Li, Xingwei
supporting information, p. 7038 - 7043 (2021/09/18)
Enantioenriched allenes are important building blocks. While they have been accessed by other coupling methodologies, enantioenriched allenes have been rarely obtained via C-H activation. In this work, kinetic resolution of tertiary propargyl alcohols as an allenylating reagent has been realized via rhodium(III)-catalyzed C-H allenylation of benzamides. The reaction proceeded efficiently under mild conditions, and both the allenylated products and the propargyl alcohols were obtained in high enantioselectivities with an s-factor of up to 139. The resolution results from bias of the two propargylic substituents and is assisted by a chiral zinc carboxylate additive.
