178963-36-5

Basic information

• Product Name: (2S,4S)-4-Amino-1-benzyl-pyrrolidine-2,4-dicarboxylic acid diethyl ester
• Synonyms: (2S,4S)-4-Amino-1-benzyl-pyrrolidine-2,4-dicarboxylic acid diethyl ester
• CAS NO: 178963-36-5
• Molecular Weight: 320.389
• Mol File: 178963-36-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,4S)-4-Amino-1-benzyl-pyrrolidine-2,4-dicarboxylic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4S)-4-Amino-1-benzyl-pyrrolidine-2,4-dicarboxylic acid diethyl ester(178963-36-5)
• EPA Substance Registry System: (2S,4S)-4-Amino-1-benzyl-pyrrolidine-2,4-dicarboxylic acid diethyl ester(178963-36-5)

Safety Data

• Hazardous Substances Data: 178963-36-5(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 911697-22-8 (S)-7-Benzyl-2,4-dioxo-1,3,7-triaza-spiro[4.4]nonane-8-carboxylic acid ethyl ester 
• 13504-85-3 (2S,4R)-1-(benzyloxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid 
• 61478-25-9 (2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid ethyl ester 
• 154342-88-8 (2S,4R)-ethyl N¹-benzyl-4-hydroxypyrrolidine-2-carboxylate 
• 154342-89-9 (2S)-ethyl N¹-benzyl-4-oxopyrrolidine-2-carboxylate 
• 103667-57-8 (2S,4R)-ethyl N¹-(benzyloxycarbonyl)-4-hydroxypyrrolidine-2-carboxylate 

Downstream Products

• 171336-79-1 (2S,4S)-4-amino-4-carboxyproline 
• 179030-56-9 (2S,4S)-1-Benzyl-4-tert-butoxycarbonylamino-pyrrolidine-2,4-dicarboxylic acid diethyl ester 

Relevant articles and documents

Synthesis of the four isomers of 4-aminopyrrolidine-2,4-dicarboxylate: Identification of a potent, highly selective, and systemically-active agonist for metabotropic glutamate receptors negatively coupled to adenylate cyclase

The four isomers of 4-aminopyrrolidine-2,4-dicarboxylate (APDC) were prepared and evaluated for their effects at glutamate receptors in vitro. (2R,4R)-APDC (2a), an aza analog of the nonselective mGluR agonist (1S,3R)- 1-aminocyclopentane-1,3-dicarboxylat