162809-97-4

Basic information

• Product Name: 2'-O-(tert-butyldimethylsilyl)-10-deacetyl-7-O-triethylsilylpaclitaxel
• Synonyms: 2'-O-(tert-butyldimethylsilyl)-10-deacetyl-7-O-triethylsilylpaclitaxel
• CAS NO: 162809-97-4
• Molecular Weight: 1040.41
• Mol File: 162809-97-4.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2'-O-(tert-butyldimethylsilyl)-10-deacetyl-7-O-triethylsilylpaclitaxel(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-O-(tert-butyldimethylsilyl)-10-deacetyl-7-O-triethylsilylpaclitaxel(162809-97-4)
• EPA Substance Registry System: 2'-O-(tert-butyldimethylsilyl)-10-deacetyl-7-O-triethylsilylpaclitaxel(162809-97-4)

Safety Data

• Hazardous Substances Data: 162809-97-4(Hazardous Substances Data)

Upstream product

• 994-30-9 triethylsilyl chloride 
• 162375-26-0 2'-O-(tert-butyldimethylsilyl)-10-deacetylpaclitaxel 
• 33069-62-4 taxol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 114655-02-6 2'-O-(tert-butyldimethylsilyl)paclitaxel 
• 78432-77-6 10-deacetylpaclitaxel 

Downstream Products

• 162664-54-2 2'-O-TBDMS-7-O-TES-9,10-diketo-paclitaxel 
• 371212-66-7 C₆₄H₈₀N₂O₁₆Si₂ 
• 849206-45-7 2'-O-TBS,7-O-TES,10-O-deacetyl-paclitaxel-10-O-carbonyl-imidazole 
• 886769-93-3 C₆₈H₁₀₁N₅O₁₄Si₂ 

Relevant articles and documents

Syntheses of Novel C-9 and C-10 Modified Bioactive Taxanes

A method has been developed for the syntheses of hitherto unreported C-9 and C-10 modified taxanes.These analogs demonstrated excellent to good cytotoxicity against B 16 melanoma cells.

BIOLOGICALLY ACTIVE TAXANE ANALOGS AND METHODS OF TREATMENT BY ORAL ADMINISTRATION

The present invention relates to a novel chemical compound of formula S-(I) for use in the treatment of cancer, to compositions containing said compound, methods of manufacture and combinations with other therapeutic agents.

Biologically Active Taxane Analogs and Methods of Treatment

The present application relates to new taxane analogs, pharmaceutical compositions comprising such analogs and methods of treating cancer comprising such compositions. The compounds according to the present application have the general formula: wherein R

9,10-alpha,alpha-OH-TAXANE ANALOGS AND METHODS FOR PRODUCTION THEREOF

The present invention relates to new taxane analogs useful for the treatment of cancer as well as methods for producing the same. The chemical compounds according to the present invention have the general Formula (I) wherein R1 and R2 are each selected fr