162375-26-0

Basic information

• Product Name: 2'-O-(tert-butyldimethylsilyl)-10-deacetylpaclitaxel
• Synonyms: 2'-O-(tert-butyldimethylsilyl)-10-deacetylpaclitaxel
• CAS NO: 162375-26-0
• Molecular Weight: 926.146
• Mol File: 162375-26-0.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 2'-O-(tert-butyldimethylsilyl)-10-deacetylpaclitaxel(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-O-(tert-butyldimethylsilyl)-10-deacetylpaclitaxel(162375-26-0)
• EPA Substance Registry System: 2'-O-(tert-butyldimethylsilyl)-10-deacetylpaclitaxel(162375-26-0)

Safety Data

• Hazardous Substances Data: 162375-26-0(Hazardous Substances Data)

Upstream product

• 114655-02-6 2'-O-(tert-butyldimethylsilyl)paclitaxel 
• 78432-77-6 10-deacetylpaclitaxel 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 33069-62-4 taxol 

Downstream Products

• 162809-97-4 2'-O-(tert-butyldimethylsilyl)-10-deacetyl-7-O-triethylsilylpaclitaxel 
• 709673-63-2 C₅₅H₇₁NO₁₃S₂Si 
• 455252-53-6 2'-O-(tert-butyldimethylsilyl)-7-chloroacetyl-10-deacetylpaclitaxel 
• 849206-45-7 2'-O-TBS,7-O-TES,10-O-deacetyl-paclitaxel-10-O-carbonyl-imidazole 
• 886769-93-3 C₆₈H₁₀₁N₅O₁₄Si₂ 
• 709673-79-0 7,10-methylthiomethyl-10-deacetylbaccatin III 
• 709673-74-5 C₃₆H₅₂O₁₀S₂Si 
• 386230-13-3 7-chloroacetyl-10-deacetylpaclitaxel 
• 162664-56-4 2'-O-TBDMS-7-O-TES-9,10-α,α-OH-9-desoxo-10-deacetylpaclitaxel 
• 162664-58-6 2'-TBS-10-deacetyl-7-TES-9α-hydroxy-10-ketopaclitaxel 
• 162664-54-2 2'-O-TBDMS-7-O-TES-9,10-diketo-paclitaxel 

Relevant articles and documents

Synthesis and cytotoxicity of 7,9-O-linked macrocyclic C-Seco taxoids

A series of novel 7,9-O-linked macrocyclic taxoids together with modification at the C2 position were synthesized, and their cytotoxicities against drug-sensitive and P-glycoprotein and βIII-tubulin overexpressed drug-resistant cancer cell lines were eval

BIOLOGICALLY ACTIVE TAXANE ANALOGS AND METHODS OF TREATMENT BY ORAL ADMINISTRATION

The present invention relates to a novel chemical compound of formula S-(I) for use in the treatment of cancer, to compositions containing said compound, methods of manufacture and combinations with other therapeutic agents.

Biologically Active Taxane Analogs and Methods of Treatment

The present application relates to new taxane analogs, pharmaceutical compositions comprising such analogs and methods of treating cancer comprising such compositions. The compounds according to the present application have the general formula: wherein R