1514888-56-2 Usage
Description
S1P receptor agonist 1 is a chemical compound that acts as an agonist for the sphingosine-1-phosphate (S1P) receptor, specifically targeting the S1P1 receptor subtype. It binds to the S1P1 receptor and activates it, leading to a series of downstream signaling events in the cell. S1P1 receptors are known to play a role in various physiological processes such as immune function, vascular development, and neural cell migration.
Uses
Used in Pharmaceutical Industry:
S1P receptor agonist 1 is used as a therapeutic agent for the development of treatments for autoimmune diseases, cardiovascular disorders, and neurological disorders. Its activation of the S1P1 receptor subtype can modulate immune function, vascular development, and neural cell migration, making it a promising candidate for these conditions.
Used in Research and Drug Discovery:
S1P receptor agonist 1 is used as a research tool for studying the role of S1P receptor signaling in various physiological processes. It can help researchers understand the mechanisms of action and potential therapeutic applications of S1P receptor agonists, contributing to the development of new drugs and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 1514888-56-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,5,1,4,8,8 and 8 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1514888-56:
(9*1)+(8*5)+(7*1)+(6*4)+(5*8)+(4*8)+(3*8)+(2*5)+(1*6)=192
192 % 10 = 2
So 1514888-56-2 is a valid CAS Registry Number.
1514888-56-2Relevant articles and documents
ADDITION SALT OF S1P1 RECEPTOR AGONIST AND CRYSTAL FORM THEREOF, AND PHARMACEUTICAL COMPOSITION
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Paragraph 0128-0129, (2021/07/31)
Disclosed in the present application are a salt form and a crystal form of an S1P1 receptor mediated disease or symptom drug 1-{2-fluoro-4-[5-(4-isobutylphenyl)-1,2,4-oxadiazole-3-yl]benzyl}-3-azetidinecarboxylic acid (formula A). Also disclosed in the present invention are a preparation method for the salt form or the crystal form, a pharmaceutical composition of the salt form or the crystal form, and use of the salt form or the crystal form in the preparation of a drug for treating and/or preventing an S1P1 receptor mediated disease or symptom.
IMMUNE ADJUSTMENT COMPOUND, USE THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
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, (2016/08/29)
The present invention provides a compound represented by formula I, wherein R is a halogen element or a C1-C6 alkyl group. The compound has S1 P1 receptor agonist activity and selective specificity and has obviously-shortened half-life in-vivo, and therefore the compound is a high-quality second-generation S1P1 receptor agonist. The present invention also provides a use of the compound in preparing medicine for treating diseases or symptoms mediated by an S1P1 receptor, a pharmaceutical composition comprising the compound, and uses of the compound and the pharmaceutical composition in treating diseases or symptoms mediated by the S1 P1 receptor.
