1452849-40-9

Basic information

• Product Name: N-(4-(6,7-dihydroxy-2-methylquinolin-3-yloxy)phenyl)-4-morpholino-3-(trifluoromethyl)benzamide
• Synonyms: N-(4-(6,7-dihydroxy-2-methylquinolin-3-yloxy)phenyl)-4-morpholino-3-(trifluoromethyl)benzamide
• CAS NO: 1452849-40-9
• Molecular Weight: 539.511
• Mol File: 1452849-40-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-(6,7-dihydroxy-2-methylquinolin-3-yloxy)phenyl)-4-morpholino-3-(trifluoromethyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-(6,7-dihydroxy-2-methylquinolin-3-yloxy)phenyl)-4-morpholino-3-(trifluoromethyl)benzamide(1452849-40-9)
• EPA Substance Registry System: N-(4-(6,7-dihydroxy-2-methylquinolin-3-yloxy)phenyl)-4-morpholino-3-(trifluoromethyl)benzamide(1452849-40-9)

Safety Data

• Hazardous Substances Data: 1452849-40-9(Hazardous Substances Data)

Upstream product

• 22608-87-3 2-amino-4,5-dimethoxybenzaldehyde 
• 6698-72-2 1-(4-nitrophenoxy)propan-2-one 
• 1452849-32-9 6,7-dimethoxy-2-methyl-3-(4-nitrophenoxy)quinoline 
• 1452849-33-0 4-(6,7-dimethoxy-2-methylquinolin-3-yloxy)benzenamine 
• 1452849-36-3 N-(4-(6,7-dimethoxy-2-methylquinolin-3-yloxy)phenyl)-4-morpholino-3-(trifluoromethyl)benzamide 

Relevant articles and documents

Optimization of the reaction conditions for synthesis of 3-(aryloxy)quinoline derivatives via friedlaender's cyclization reaction

6,7-Dimethoxy-2-methyl-3-(4-nitrophenoxy)quinoline was synthesized by Friedlaender's cyclization reaction. Different bases and solvents were tested in order to optimize the reaction conditions. The highest yields were obtained using piperidine in refluxin