1452849-36-3Relevant articles and documents
Optimization of the reaction conditions for synthesis of 3-(aryloxy)quinoline derivatives via friedlaender's cyclization reaction
Khan, Mohammad Ashrafuddin,El-Gamal, Mohammed I.,Oh, Chang-Hyun
, p. 1848 - 1852 (2013/07/26)
6,7-Dimethoxy-2-methyl-3-(4-nitrophenoxy)quinoline was synthesized by Friedlaender's cyclization reaction. Different bases and solvents were tested in order to optimize the reaction conditions. The highest yields were obtained using piperidine in refluxin