1447814-82-5Relevant articles and documents
PROCESS FOR THE SYNTHESIS OF ETORICOXIB
-
Page/Page column 20; 21, (2013/07/25)
The present invention relates to a process for the synthesis of the anti-inflammatory agent 5-chloro-3-(4-methanesulfonylphenyl)-6'-methyl-[2,3']bipyridine, referred to as compound of formula (1) or etoricoxib, which is a pharmaceutically active ingredient inhibiting cyclooxygenase-2. In particular, the application concerns a novel process of making the compound of formula (1) by oxidizing a compound of formula (4).