1441306-37-1

Basic information

• Product Name: methyl 2-((3-bromonaphthalen-2-yl)(hydroxy)methyl)acrylate
• Synonyms: methyl 2-((3-bromonaphthalen-2-yl)(hydroxy)methyl)acrylate
• CAS NO: 1441306-37-1
• Molecular Weight: 321.17
• Mol File: 1441306-37-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 2-((3-bromonaphthalen-2-yl)(hydroxy)methyl)acrylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-((3-bromonaphthalen-2-yl)(hydroxy)methyl)acrylate(1441306-37-1)
• EPA Substance Registry System: methyl 2-((3-bromonaphthalen-2-yl)(hydroxy)methyl)acrylate(1441306-37-1)

Safety Data

• Hazardous Substances Data: 1441306-37-1(Hazardous Substances Data)

Upstream product

• 89005-11-8 3-bromo-2-naphthalenecarboxaldehyde 
• 292638-85-8 acrylic acid methyl ester 

Downstream Products

• 1441307-16-9 methyl 1-phenyl-1,2-dihydrobenzo[g]quinoline-3-carboxylate 

Relevant articles and documents

Palladium-catalyzed arylic/allylic aminations: Permutable domino sequences for the synthesis of dihydroquinolines from morita-baylis-hillman adducts

An efficient palladium-catalyzed synthesis of 1,2-dihydroquinolines has been developed via the reaction between anilines and Morita-Baylis-Hillman adducts derived from o-bromobenzaldehyde. This new Pd(0)-catalyzed pseudo-domino type I sequence involves a Buchwald-Hartwig arylic amination and an allylic amination. When starting from an o-bromo allylic alcohol, the chronology is arylic amination/allylic arylation. However, the sequence reverses when the reaction is performed on the corresponding o-bromo allylic acetate.