130799-25-6

Basic information

• Product Name: (S)-2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-formyl-amino]-benzoylamino}-pentanedioic acid 1-tert-butyl ester
• CAS NO: 130799-25-6
• Molecular Weight: 524.536
• Mol File: 130799-25-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-formyl-amino]-benzoylamino}-pentanedioic acid 1-tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-formyl-amino]-benzoylamino}-pentanedioic acid 1-tert-butyl ester(130799-25-6)
• EPA Substance Registry System: (S)-2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-formyl-amino]-benzoylamino}-pentanedioic acid 1-tert-butyl ester(130799-25-6)

Safety Data

• Hazardous Substances Data: 130799-25-6(Hazardous Substances Data)

Upstream product

• 89043-75-4 4-amino-4-deoxy-N¹⁰-formylpteroic acid 
• 34582-33-7 α-tert-butyl γ-methyl L-glutamate hydrochloride 
• 130799-24-5 (S)-2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-formyl-amino]-benzoylamino}-5-oxo-hexanoic acid tert-butyl ester 

Relevant articles and documents

Synthesis and Biological Activity of Methotrexate Analogues with Two Acid Groups and a Hydrophobic Aromatic Ring in the Side Chain

The heretofore unknown γ-(m-carboxylanilide) and γ-(m-boronoanilide) derivatives of methotrexate (MTX) and γ-(m-carboxyanilide) derivatives of aminopterin (AMT) were prepared and tested as inhibitors of dihydrofolate reductase (DHFR) and as inhibitors of