106004-06-2Relevant articles and documents
Convenient one-pot preparation of dimethyl bicyclo[2.2.2]octane-1,4- dicarbolylate, a key intermediate for a novel adenosine A1 receptor antagonist
Chang, HeXi,Kiesman, William F.,Petter, Russell C.
, p. 1267 - 1272 (2007)
Dimethyl bicyclo[2.2.2]octane-1,4-dicarboxylate (4), a key starting material for a novel adenosine A1 receptor antagonist, was prepared in a one-pot reaction with convenient workup and improved yield. Copyright Taylor & Francis Group, LLC.
SUBSTITUTED DIAMINOCARBOXAMIDE AND DIAMINOCARBONITRILE PYRIMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
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Page/Page column 134; 135, (2012/11/07)
Provided herein are Diaminopyrimidine Compounds having the following structures: wherein R1, R2, R3, and R4 are as defined herein, compositions comprising an effective amount of a Diaminopyrimidine Compound, and methods for treating or preventing liver fibrotic disorders or a condition treatable or preventable by inhibition of a JNK pathway.
HETEROBICYCLIC METALLOPROTEASE INHIBITORS
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Page/Page column 176-177, (2008/12/05)
The present invention relates generally to heterobicyclic containing pharmaceutical agents, and in particular, to heterobicyclic metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of heterobicyclic metalloprotease inhibiting compounds that exhibit an increased potency in relation to currently known metalloprotease inhibitors.