107-04-0

Basic information

• Product Name: 1-Bromo-2-chloroethane
• Synonyms: 1-Bromo-2-chloroethane, 98+%;1-BROMO-2-CHLOROETHANE pure;Ethylene bromochloride, Ethylene chlorobromide;1-Bromo-2-chloroetha;1-BroMo-2-chloroethane, 98% 100ML;2-Bromoethyl Chloride 2-Chloroethyl Bromide;1 - broMine - 2 - ethyl chloride;1-BroMo-2-chlo
• CAS NO: 107-04-0
• Molecular Formula: C₂H₄BrCl
• Molecular Weight: 143.41
• EINECS: 203-456-0
• Product Categories: omega-Haloalkyl Chlorides;omega-Functional Alkanols, Carboxylic Acids, Amines & Halides;Alkyl;Building Blocks;Chemical Synthesis;Halogenated Hydrocarbons;Organic Building Blocks;API Intermediate
• Mol File: 107-04-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: −18-−14 °C(lit.)
• Boiling Point: 106-107 °C(lit.)
• Flash Point: 104-107°C
• Appearance: Clear colorless to slightly yellow/Liquid
• Density: 1.723 g/mL at 25 °C(lit.)
• Vapor Pressure: 32.6mmHg at 25°C
• Refractive Index: n20/D 1.4884(lit.)
• Storage Temp.: Store below +30°C.
• Solubility: water: soluble
• Water Solubility: 7 g/L (20 ºC)
• Sensitive: Light Sensitive
• BRN: 605265
• CAS DataBase Reference: 1-Bromo-2-chloroethane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Bromo-2-chloroethane(107-04-0)
• EPA Substance Registry System: 1-Bromo-2-chloroethane(107-04-0)

Safety Data

• Hazard Codes: T
• Statements: 45-20/21-25-37/38-68-36/37/38-23/25
• Safety Statements: 53-36/37-45-38-36/37/39-28A
• RIDADR: UN 2810 6.1/PG 2
• WGK Germany: 3
• RTECS: KH6500000
• TSCA: Yes
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 107-04-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
1-Bromo-2-chloroethane is used as an intermediate for organic synthesis, particularly in the regioand diastereoselective synthesis of 2-alkylidenetetrahydrofurans.
Used as a Solvent:
1-Bromo-2-chloroethane is used as a solvent in various chemical processes due to its properties as a clear colorless liquid.
Used in Fumigation:
1-Bromo-2-chloroethane is also used as a fumigant in different industries, providing a means to control pests and maintain product quality.

Air & Water Reactions

Slightly water soluble.

Reactivity Profile

1-Bromo-2-chloroethane is incompatible with strong bases, strong oxidizing agents and magnesium .

Fire Hazard

Literature sources indicate that 1-Bromo-2-chloroethane is nonflammable.

Purification Methods

Wash it with conc H2SO4, water, 10% Na2CO3 solution, and again with water, then dry with CaCl2 and fractionally distil before use. [Beilstein 1 H 89, 1 I 28, 1 II 61, 1 III 179, 1 IV 155.]

InChI:InChI=1S/C2H4BrCl/c3-1-2-4/h1-2H2

Upstream product

• 693-03-8 n-butyl magnesium bromide 
• 60-29-7 diethyl ether 
• 5411-48-3 sulfuric acid bis-(2-chloroethyl) ester 
• 74-85-1 ethene 
• 107-06-2 1,2-dichloro-ethane 
• 106-93-4 ethylene dibromide 
• 107-07-3 2-chloro-ethanol 
• 79-15-2 N-bromoacetamide 
• 6738-06-3 phenylethynylmagnesium bromide 
• 80-41-1 2-chloroethyl tosylate 
• 75-09-2 dichloromethane 
• 109-69-3 n-Butyl chloride 
• 543-59-9 1-Chloropentane 
• 544-10-5 1-Chlorohexane 

Downstream Products

• 91724-42-4 6-(2-chloro-ethylmercapto)-7(9)H-purine 
• 79172-43-3 1-benzoylcyclopropanecarboxylic acid 
• 54373-15-8 4-(2-chloroethoxy)benzaldehyde 
• 108-86-1 bromobenzene 
• 74-85-1 ethene 
• 37858-32-5 dithiophosphoric acid O,O'-diethyl ester-S-(2-chloro-ethyl ester) 
• 1932-03-2 2-(piperidin-4-yl)ethyl chloride 
• 131728-48-8 1-(2-chloroethyl)-1,3-dihydro-2H-indol-2-one 
• 96450-55-4 1-(β-chloroethyl)-3-methylpyrazole 
• 72874-20-5 8-Chloro-2-(2-chloro-ethyl)-6-(2-chloro-phenyl)-2,4-dihydro-2,3,5,10b-tetraaza-benzo[e]azulen-1-one 
• 104072-03-9 1-(2-Chloro-ethyl)-4-phenethyl-1,4-dihydro-tetrazol-5-one 
• 104072-02-8 1-(2-Chloro-ethyl)-4-cyclohexyl-1,4-dihydro-tetrazol-5-one 
• 56413-00-4 1-benzyl-4-(2-chloro-ethyl)-1,4-dihydro-tetrazol-5-one 
• 858004-40-7 2-(2-chloro-ethyl)-2-phenyl-hexanenitrile 

Related news

Regular articleExcess volumes of (bromochloromethane or 1-Bromo-2-chloroethane (cas 107-04-0) + heptane or cyclohexane or benzene or tetrachloromethane) at the temperature 298.15 K08/26/2019

Excess molar volumesVEmof [x(BrCH2ClorBrCH2CH2Cl) + (1 -x){CH3(CH2)5CH3orc-(CH2)6or C6H6or CCl4}] have been determined from density measurements at the temperature 298.15 K, using a vibrating-tube densimeter. Excess molar volumesVEmfor these mixtures are positive, but noticeably less positive wh...detailed

Molecular and dissociative adsorption of 1-Bromo-2-chloroethane (cas 107-04-0) on Cu(111)08/22/2019

The adsorption of 1-bromo-2-chloroethane (BCE) on Cu(111) in the temperature range 100–300 K has been studied using ultraviolet photoelectron spectroscopy (UPS), work function measurements, low energy electron diffraction, and line of sight temperature programmed desorption (LOSTPD). At 300 K a...detailed

Photodissociation of 1-Bromo-2-chloroethane (cas 107-04-0) at 266 nm08/21/2019

The photodissociation of CH2BrCH2Cl at 266 nm has been investigated on the universal crossed molecular beam machine. The primary dissociation step leads exclusively to the formation of CH2CH2Cl radicals and Br atoms in the electronic ground state as well as in the spin–orbit excited state, with...detailed

The surface structure of 1-Bromo-2-chloroethane (cas 107-04-0) on Cu(111)08/20/2019

The structure of 1-bromo-2-chloroethane (BCE) molecularly adsorbed on Cu(111) and the adsorption sites of chemisorbed chlorine and bromine coadsorbed with the BCE have been determined using the normal incidence X-ray standing wave (NIXSW) method. Two Bragg reflections, the (111) and (1¯11), wer...detailed

Asymmetry in the internal energies of the optical rotamers of 1-Bromo-2-chloroethane (cas 107-04-0) in oriented-molecule/surface scattering: A classical molecular dynamics study08/19/2019

The internal energy excitation and relaxation of oriented G, G′, and T rotamers of 1-bromo-2-chloroethane colliding with a model surface were studied by classical molecular dynamics. For a given oriented molecule colliding with a surface at an incident angle, the distributions of the final rota...detailed

Relevant articles and documents

Facile continuous process for gas phase halogen exchange over supported alkyl phosphonium salts

Chloride-bromide halogen exchange was realized when a mixture of an alkyl chloride and an alkyl bromide were reacted over a supported molten alkyl phosphonium catalyst. Conversion was found to be near equilibrium in a tubular flow reactor at 150 °C and 1500 GHSV. The catalyst was prepared by impregnation of alumina or silica support and found to be highly stable for relatively long periods of time. A pathway for the catalytic cycle is proposed.

Reactivity of [WCl6] with Ethers: A Joint Computational, Spectroscopic and Crystallographic Study

The reactions of [WCl6] with a series of ethers have been performed in chlorinated solvent and elucidated by means of analytical, spectroscopic and DFT methods. The addition of tetrahydropyran (thp) or 1,4-dioxane to [WCl6] resulted in the reversible formation of the adducts WCl6···L [L = thp (1a), 1,4-dioxane (1b)], detected in solution by NMR spectroscopy. The reaction of [WCl6] with thp in a molar ratio of 1:2 in chloroform at reflux afforded [WOCl4(thp)] (2a), which was isolated in 51 % yield. [WOCl4(OMe2)] (2b) and [WOCl3(OMe2)2] (3a) were isolated in yields of 53 and 18 %, respectively, from the reaction of [WCl6] with an excess of dimethyl ether. [WOCl3(OEt2)2] (3b) was the only identified metal compound produced from the reaction of [WCl6] and OEt2(1:2 molar ratio). According to NMR studies, the oxide ligand in 2a,b and 3a,b was generated by double C–O bond cleavage involving one equivalent of organic reactant. The 1:1 reaction of [WCl6] with 1,2-diethoxyethane led to [WCl5(κ1-OCH2CH2OEt)] (4) and a minor amount of [WCl4(κ2-EtOCH2CH2OEt)] (5). The aryl oxide compound [WCl5(OPh)] (6) was prepared in 62 % yield from the reaction of [WCl6] and anisole by selective Csp3–O bond activation. The prolonged heating of a mixture of [WCl6] and diphenyl ether in 1,2-dichloroethane led to the isolation of the WVcomplex [WCl5(OPh2)] (7). The molecular structures of 2a and 3a were ascertained by X-ray diffraction.