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Basic Information
CAS No.: 80621-81-4
Name: Rifaximin
Article Data: 1
Molecular Structure:
Molecular Structure of 80621-81-4 (Rifaximin)
Formula: C43H51N3O11
Molecular Weight: 785.891
Synonyms: L 105;L 105(ansamacrolide antibiotic);L 105SV;Rifamycin L 105;Rifamycin L 105SV;Xifaxan;refaximin;
EINECS: 617-130-4
Density: 1.366 g/cm3
Melting Point: 200-205 °C(dec)
Appearance: Red-orange crystalline powder
PSA: 198.38000
LogP: 6.29580
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With ascorbic acid
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Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: CHCl3 / 2 h / Ambient temperature
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View Scheme
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ConditionsYield
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Raw Materials
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    Xi'an HDM Biotech Co., Ltd. was established in 2012. It is a high-tech professional and technical enterprise integrating R & D, production and sales. Located in the world-famous hi

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    Rifaximin

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    80621-81-4

    Rifaximin CAS.80621-81-4 high quality, ready stock, competitive price

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    Rifaximin CAS.80621-81-4 high quality, ready stock, competitive priceAppearance:Orange powder. Storage:Room temperature. Package:according to customers' requirements Application:This medication is used to treat diarrhea caused by the common bacteria

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    80621-81-4

    Rifaximin

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  • Rifaximin

  • Casno:

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    Rifaximin

    Min.Order: 10 Gram

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Chemistry

Structure of Rifaximin (CAS NO.80621-81-4):

Empirical Formula: C43H51N3O11
Molecular Weight: 785.8785 
Index of Refraction: 1.634
Molar Refractivity: 205.697 cm3
Molar Volume: 575.317 cm3
Polarizability: 81.545×10-24cm3
Surface Tension: 48.156 dyne/cm
Density: 1.366 g/cm3 
Melting Point: 200-205°C(dec) 
Physical Appearance: Red-Orange Crystalline Powder
Product Categories: Active Pharmaceutical Ingredients;Antibacterial;Intermediates & Fine Chemicals;Pharmaceuticals 
Synonyms of Rifaximin (CAS NO.80621-81-4):  (2S,16Z,18E,20S,21S,22R,23R,24R,25S,26S,27S,28E)-5,6,21,23,25 Pentahydroxy-27-methoxy-2,4,11,16,20,22,24,26-octamethyl-2,7-(epoxypentadeca(1,11,13)trienimino)benzofuro(4,5-e)pyrido(1,2-a)benzimidazole-1,15(2H)-dione, 25-acetate ; 4-Deoxy-4'-methylpyrido(1',2'-1,2)imidazo(5,4-c)rifamycin SV ; Fatroximin ; Normix ; Rifacol .

Uses

 Rifaximin (CAS NO.80621-81-4) is highly effective at preventing and treating traveler's diarrhea among travelers to Mexico, with few side effects and low risk of developing antibiotic resistance. In the United States, Rifaximin has orphan drug status for the treatment of hepatic encephalopathy.

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral > 2gm/kg (2000mg/kg)   Drugs of the Future. Vol. 7, Pg. 260, 1982.
rat LD50 oral > 2gm/kg (2000mg/kg)   Chemioterapia. Vol. 5, Pg. 263, 1986.

Safety Profile

RTECS: KD1576000