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CAS No.: | 67027-56-9 |
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Name: | meclonazepam |
Article Data: | 3 |
Molecular Structure: | |
Formula: | C16H12ClN3O3 |
Molecular Weight: | 329.743 |
Synonyms: | Meclonazepam;5-(2-Chlorophenyl)-1,3-dihydro-3-methyl-7-nitro-2H-1,4-benzodiazepin-2-one;(RS)-Ro 11-3128/002;2H-1,4-Benzodiazepin-2-one, 5-(2-chlorophenyl)-1,3-dihydro-3-methyl-7-nitro-;Ro 11-3128/002;67027-56-9; |
Density: | 1.46g/cm3 |
Boiling Point: | 522.1°Cat760mmHg |
Flash Point: | 269.6°C |
PSA: | 90.77000 |
LogP: | 3.47010 |
(+)-5-(o-chlorophenyl)-1,3-dihydro-3-methyl-7-nitro-2H-1,4-benzodiazepin-2-one
C16H14ClN3O3
Conditions | Yield |
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With sodium cyanoborohydride; acetic acid In tetrahydrofuran | 90% |
(+)-5-(o-chlorophenyl)-1,3-dihydro-3-methyl-7-nitro-2H-1,4-benzodiazepin-2-one
C16H14ClN3O
Conditions | Yield |
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With hydrogenchloride; tin In ethanol Heating; | 50% |
(+)-5-(o-chlorophenyl)-1,3-dihydro-3-methyl-7-nitro-2H-1,4-benzodiazepin-2-one
5-(2-chloro-phenyl)-3-methyl-7-nitro-1,3-dihydro-benzo[e][1,4]diazepine-2-thione
Conditions | Yield |
---|---|
With Lawessons reagent In tetrahydrofuran | 10% |
With diphosphorus pentasulfide; triethylamine In 1,4-dioxane; dichloromethane; ethyl acetate |
(+)-5-(o-chlorophenyl)-1,3-dihydro-3-methyl-7-nitro-2H-1,4-benzodiazepin-2-one
methyl iodide
Conditions | Yield |
---|---|
With potassium carbonate In ethanol; dichloromethane; acetone |