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CAS No.: | 6323-18-8 |
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Name: | 2-chloropropiophenone |
Article Data: | 13 |
Molecular Structure: | |
Formula: | C9H9 Cl O |
Molecular Weight: | 168.623 |
Synonyms: | Propiophenone,2'-chloro- (6CI,7CI); 2'-Chloropropiophenone; NSC 32597; o-Chloropropiophenone |
Density: | 1.128±0.06 g/cm3(Predicted) |
Boiling Point: | 115-116℃ (15 Torr) |
PSA: | 17.07000 |
LogP: | 2.93270 |
2-chloro-α-ethylbenzyl alcohol
2-chloropropiophenone
Conditions | Yield |
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With pyridinium chlorochromate In dichloromethane at 20℃; for 2h; | 99% |
With chromium(VI) oxide; sulfuric acid In acetone for 2h; | |
With chromium(VI) oxide; sulfuric acid In water; acetone at 10℃; Jones oxidation; |
Conditions | Yield |
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Stage #1: 2-Chlorobenzonitrile; ethylmagnesium bromide Stage #2: With water Further stages.; | 89% |
Stage #1: 2-Chlorobenzonitrile; ethylmagnesium bromide Stage #2: With sulfuric acid | 79% |
Conditions | Yield |
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With hydrogenchloride; copper(l) chloride at 70℃; |
Conditions | Yield |
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(i), (ii) aq. H2SO4; Multistep reaction; |
methyl-malonic acid dimethylester
o-chlorobenzoyl chloride
2-chloropropiophenone
Conditions | Yield |
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(i) Mg, I2, EtOH, CCl4, benzene, (ii) /BRN= 386435/; Multistep reaction; |
Conditions | Yield |
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Multi-step reaction with 2 steps 1.1: tetrahydrofuran / 0.33 h / -78 - 20 °C 1.2: 65 percent / 4 h / 20 °C 2.1: 99 percent / PCC / CH2Cl2 / 2 h / 20 °C View Scheme |
Conditions | Yield |
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Multi-step reaction with 2 steps 1: diethyl ether 2: CrO3; H2SO4 / acetone; H2O / 10 °C View Scheme |
2-Chlorobenzonitrile
A
2-chloropropiophenone
B
2-bromo-2'-chloropropiophenone
Conditions | Yield |
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With aluminium trichloride at 40℃; |
Conditions | Yield |
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With C34H27IrN2P(1+)*C32H12BF24(1-); caesium carbonate at 65℃; for 24h; Inert atmosphere; | 89% |