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CAS No.: | 5323-58-0 |
---|---|
Name: | 6-methoxy-8-nitroquinolin-5(1H)-one |
Article Data: | 1 |
Molecular Structure: | |
Formula: | C10H8 N2 O4 |
Molecular Weight: | 220.185 |
Synonyms: | 5-Hydroxy-6-methoxy-8-nitroquinoline;NSC 2785 |
Density: | 1.44g/cm3 |
Boiling Point: | 403.4°Cat760mmHg |
Flash Point: | 197.7°C |
PSA: | 88.17000 |
LogP: | 2.38040 |
Conditions | Yield |
---|---|
With hydrogenchloride; sodium hydroxide In water | 90% |
With potassium hydroxide | |
With hydrogenchloride | |
With hydrogenchloride |
6-methoxy-8-nitro-quinolin-5-ol
Conditions | Yield |
---|---|
With sodium hydroxide |
Conditions | Yield |
---|---|
With arsenic(V) oxide; sulfuric acid at 130 - 140℃; |
N-(5-fluoro-4-methoxy-2-nitrophenyl)acetamide
glycerol
A
5-fluoro-6-methoxy-8-nitroquinoline
B
6-methoxy-8-nitro-quinolin-5-ol
Conditions | Yield |
---|---|
With arsenic(V) oxide; sulfuric acid |
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: acetic acid anhydride; glacial acetic acid; HNO3 / -10 - 0 °C 2: platinum / Hydrogenation 3: concentrated sulfuric acid; water; nitric acid 4: arsenic (v)-oxide; sulfuric acid View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: platinum / Hydrogenation 2: concentrated sulfuric acid; water; nitric acid 3: arsenic (v)-oxide; sulfuric acid View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: concentrated sulfuric acid; water; nitric acid 2: arsenic (v)-oxide; sulfuric acid View Scheme |
4-Acetylamino-1,2-dimethoxy-5-nitrobenzene
6-methoxy-8-nitro-quinolin-5-ol
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: arsenic (V)-oxide; concentrated sulfuric acid 2: aq.-ethanolic hydrochloric acid View Scheme |
1-bromo-octane
6-methoxy-8-nitro-quinolin-5-ol
6-Methoxy-8-nitro-5-(n-octoxy)quinoline
Conditions | Yield |
---|---|
With N,N,N,N,N,N-hexamethylphosphoric triamide; triethylamine; methyloxirane at 140 - 150℃; for 2.5h; | 75% |
With triethylamine; methyloxirane In N,N,N,N,N,N-hexamethylphosphoric triamide; diethyl ether |
amyl iodide
6-methoxy-8-nitro-quinolin-5-ol
6-Methoxy-8-nitro-5-pentyloxy-quinoline
Conditions | Yield |
---|---|
With N,N,N,N,N,N-hexamethylphosphoric triamide; triethylamine; methyloxirane at 140 - 150℃; for 2.5h; | 73% |