Products Categories
CAS No.: | 1593-60-8 |
---|---|
Name: | N-Hydroxy-4-methylbenzenesulfonamide |
Article Data: | 12 |
Molecular Structure: | |
Formula: | C7H9NO3S |
Molecular Weight: | 187.219 |
Synonyms: | N-Hydroxy-4-toluenesulfonamide;N-hydroxyl-4-toluenesulfonamide;toluenesulfohydroxamic acid;Hydroxysulfonamide 58;N-tosyl hydroxylamine; |
Density: | 1.363 |
Melting Point: | 126-128℃ (DEC.) |
Boiling Point: | 355.6±35.0 °C(Predicted) |
PSA: | 74.78000 |
LogP: | 2.13420 |
Conditions | Yield |
---|---|
With hydroxylamine hydrochloride; magnesium oxide In tetrahydrofuran; methanol; water at 20℃; | 87.5% |
With hydroxylamine hydrochloride; magnesium oxide In methanol; water at 20℃; for 2h; chemoselective reaction; | 85% |
With hydroxylamine hydrochloride; magnesium oxide In tetrahydrofuran; methanol; water at 25℃; for 2h; Inert atmosphere; Schlenk technique; | 85% |
p-toluenesulfonylhydroxylamine
Conditions | Yield |
---|---|
With boron trifluoride diethyl etherate In methanol; dichloromethane at 20℃; for 4h; | 80% |
Conditions | Yield |
---|---|
With water; potassium carbonate; p-toluenesulfonyl chloride In tetrahydrofuran; methanol at 0 - 20℃; for 3h; | 42% |
p-Toluolsulfonylnitrit
p-toluenesulfonylhydroxylamine
Conditions | Yield |
---|---|
With sodium tetrahydroborate In 1,4-dioxane at 5 - 10℃; for 0.666667h; | 16% |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 89 percent / pyridine / CH2Cl2 / 3 h / 20 °C 2: 80 percent / BF3*OEt2 / CH2Cl2; methanol / 4 h / 20 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 54 percent / N2O4 / CCl4; diethyl ether / 0.17 h / 0 °C 2: 16 percent / NaBH4 / dioxane / 0.67 h / 5 - 10 °C View Scheme |
6-fluoro-1H-indole
p-toluenesulfonylhydroxylamine
6-fluoro-3-[(4-methylphenyl)thio]indole
Conditions | Yield |
---|---|
With 1-hydroxy-pyrrolidine-2,5-dione; iodine In butan-1-ol at 120℃; for 15h; Inert atmosphere; Sealed tube; regioselective reaction; | 99% |
p-toluenesulfonylhydroxylamine
1,1,1,3,3,3-hexamethyl-disilazane
C10H17NO3SSi
Conditions | Yield |
---|---|
With <(C6H5O)PO>2NH In dichloromethane for 0.833333h; Heating; | 98.5% |
3,4-dihydro-2H-pyran
p-toluenesulfonylhydroxylamine
O-(Tetrahydro-2H-pyran-2-yl)-N-tosylhydroxylamine
Conditions | Yield |
---|---|
In dichloromethane for 0.5h; | 98% |
indole
p-toluenesulfonylhydroxylamine
3-[(4-methylphenyl)sulfanyl]-1H-indole
Conditions | Yield |
---|---|
With 1-hydroxy-pyrrolidine-2,5-dione; iodine In butan-1-ol at 120℃; for 15h; Catalytic behavior; Solvent; Reagent/catalyst; Inert atmosphere; Sealed tube; regioselective reaction; | 98% |