benzhydryl-(2-chloro-ethyl)-sulfone

Base Information

• Chemical Name: benzhydryl-(2-chloro-ethyl)-sulfone
• CAS No.: 874506-46-4
• Molecular Formula: C₁₅H₁₅ClO₂S
• Molecular Weight: 294.802
• Mol file: 874506-46-4.mol

Synonyms:

Chemical Property of benzhydryl-(2-chloro-ethyl)-sulfone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzhydryl-(2-chloro-ethyl)-sulfone

There total 2 articles about benzhydryl-(2-chloro-ethyl)-sulfone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diphenylchloromethane (90-99-3) → benzhydryl-(2-chloro-ethyl)-sulfone (874506-46-4)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol / Versetzen des Reaktionsgemisches mit wss. NaOH, anschliessendes Erhitzen auf Siedetemperatur

2: sodium ethylate; ethanol / Erwaermen des Reaktionsprodukts in Eisessig mit wss. H₂O₂ auf 80grad

With ethanol; sodium ethanolate;

DOI:10.1021/ja01191a090

Reference yield:

diphenylmethanethiol (4237-48-3) + 1-Bromo-2-chloroethane (107-04-0) → benzhydryl-(2-chloro-ethyl)-sulfone (874506-46-4)

Guidance literature:

With ethanol; sodium ethanolate; Erwaermen des Reaktionsprodukts in Eisessig mit wss. H₂O₂ auf 80grad;

DOI:10.1021/ja01191a090

Reference yield:

benzhydryl-(2-chloro-ethyl)-sulfone (874506-46-4) → 1-ethoxy-2-diphenylmethanesulfonyl-ethane (93727-95-8)

Guidance literature:

With potassium hydroxide;

DOI:10.1021/ja01191a090

upstream raw materials:

diphenylmethanethiol

1-Bromo-2-chloroethane

diphenylchloromethane

Downstream raw materials:

1-(2-diphenylmethanesulfonyl-ethyl)-piperidine

1-ethoxy-2-diphenylmethanesulfonyl-ethane

(2-diphenylmethanesulfonyl-ethyl)-dimethyl-amine