H-ORN(Z)-OBZL HCL

Base Information

• Chemical Name: H-ORN(Z)-OBZL HCL
• CAS No.: 63594-37-6
• Molecular Formula: C20H24 N2 O4 . Cl H
• Molecular Weight: 392.87700
• Hs Code.: 2924299090
• Mol file: 63594-37-6.mol

Synonyms:Ornithine,N5-carboxy-, dibenzyl ester, hydrochloride, L- (7CI)

Chemical Property of H-ORN(Z)-OBZL HCL

Chemical Property:

• PSA: 90.65000
• LogP: 4.65690
• Storage Temp.: Store at RT.

Purity/Quality:

98.5% ^*data from raw suppliers

H-ORN(Z)-OBZLHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of H-ORN(Z)-OBZL HCL

There total 1 articles about H-ORN(Z)-OBZL HCL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (S)-2-amino-5-benzyloxycarbonylamino-pentanoic acid benzyl ester hydrochloride (63594-37-6)

Guidance literature:

Orn-Z, 1.)COCl2, 2.)Benzylalkohol, HCl;

Reference yield: 99.0%

(S)-2-amino-5-benzyloxycarbonylamino-pentanoic acid benzyl ester hydrochloride (63594-37-6) + N,N'-bis(N-(carboxymethyl))-N,N'-bis(N-(2-(4-fluorophenyl)ethyl)carboxamidomethyl)benzene-1,3-dicarboxamide (215161-79-8) → C72H76F2N8O14

Guidance literature:

With N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate; In N,N-dimethyl-formamide; at 25 ℃; for 12h;

DOI:10.1016/S0968-0896(98)00128-X

Reference yield: 92.0%

(S)-2-amino-5-benzyloxycarbonylamino-pentanoic acid benzyl ester hydrochloride (63594-37-6) + o-Nitrobenzenesulfenylproline 2,4,5-trichlorophenyl Ester (65306-41-4) → o-Nitrobenzenesulfenylprolyl-Nδ-benzyloxycarbonylornithine Benzyl Ester (88681-60-1)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; for 24h; Ambient temperature;

DOI:10.1135/cccc19832862

Downstream raw materials:

o-Nitrobenzenesulfenylprolyl-N^δ-benzyloxycarbonylornithine Benzyl Ester

(S)-3-[3-(1-benzyloxycarbonyl-4-benzyloxycarbonylaminobutyl)ureido]benzoic acid ethyl ester

3-[4-(S)-(3-tert-butoxycarbonylamino-propyl)-2,5-dioxo-imidazolidin-1-yl]benzoic acid

{3-[4-(S)-(3-tert-butoxycarbonylamino-propyl)-2,5-dioxo-imidazolidin-1-yl]benzoyl}-Asp(O-t-Bu)-(S)-phenylglycine-O-t-Bu