CID 13030078

Base Information

• Chemical Name: CID 13030078
• CAS No.: 660-68-4
• Molecular Formula: C4H11N^.HCl
• Molecular Weight: 109.599
• Hs Code.: 29211200
• Mol file: 660-68-4.mol

Synonyms:

Chemical Property of CID 13030078

Chemical Property:

• Appearance/Colour: white to off-white crystals or crystalline powder
• Vapor Pressure: <0.00001 hPa (20 °C)
• Melting Point: 227-230 °C(lit.)
• Refractive Index: 1.5320 (estimate)
• Boiling Point: 57.3 °C at 760 mmHg
• Flash Point: 320-330°C
• PSA: 12.03000
• Density: 1.0 g/mL at 20 °C
• LogP: 1.80870
• Storage Temp.: Store below +30°C.
• Sensitive.: Hygroscopic
• Solubility.: H2O: soluble50mg/mL, clear, colorless
• Water Solubility.: soluble
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 109.0658271
• Heavy Atom Count: 6
• Complexity: 15

Purity/Quality:

99% ^*data from raw suppliers

Diethylamine Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,Xi
• Hazard Codes: Xn,Xi
• Statements: 10-36/37/38
• Safety Statements: 26-39-7-24/25-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC[NH2+]CC.[Cl-]
• Uses: Diethylamine hydrochloride acts as a precursor of atrazine and lysergic acid diethylamide. It is also used as a reactant in the production of dyes and pharmaceutical compounds such as ranitidine. Further, it is used in Mannich reaction with paraformaldehyde. In addition to this, it is employed in the synthesis of diethylaminoethyl (DEAE) cottons by reacting with cotton cellulose in the presence of sodium hydroxide.

Technology Process of CID 13030078

There total 104 articles about CID 13030078 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

diethylamine (109-89-7) → diethyl amine hydrochloride (660-68-4)

Guidance literature:

With hydroxylamine hydrochloride; In ethanol; for 2h; Reflux;

DOI:10.1080/00397911.2015.1096943

Reference yield: 98.0%

bis(diethylamino)-(-)-menthylphosphine(pentacarbonyl)molybdenum(0) → chlorodiethylamino-(-)-menthylphosphine(pentacarbonyl)molybdenum(0) + diethyl amine hydrochloride (660-68-4)

Guidance literature:

With hydrogenchloride; In pentane; Under stirring a strong stream of hydrogenhalogenide is bubbled for 20 min through the soln. of phosphine complex at room temp.(inert atmosphere).; Solvent is evapd. at room temp. in vac., residue is digested with pentane, dialkylamminhydrohalogenide is filtered off, filtrate is dried to dryness in vac., chromy., elem. anal.;

DOI:10.1016/0022-328X(89)85002-8

Reference yield: 96.0%

bis(diethylamino)-(-)-menthylphosphine(pentacarbonyl)tungsten(0) → chlorodiethylamino-(-)-menthylphosphine(pentacarbonyl)tungsten(0) + diethyl amine hydrochloride (660-68-4)

Guidance literature:

With hydrogenchloride; In pentane; Under stirring a strong stream of hydrogenhalogenide is bubbled for 3-10 min through the cooled (-50-0°C) soln. of phosphine complex (inert atmosphere).; Solvent is evapd. at room temp. in vac., residue is digested with pentane, dialkylamminhydrohalogenide is filtered off, filtrate is dried to dryness in vac., recrystn. from pentane (-78°C), not purely isolated.;

DOI:10.1016/0022-328X(89)85002-8

upstream raw materials:

3-diethylaminopropionitrile

p-anisidine hydrochloride

N-chlorodiethylamine

4-chloro-valeric acid diethylamide

Downstream raw materials:

N,N-diethylnicotinamide

2,3,5-trimethylphenol

3-diethylamino-2,2-dimethyl-propionaldehyde

3-diethylaminophenol

Refernces

• 1、 Osthoff,Brown. "". . p. 2378. Retrieved 1952.
• 2、 Ghosh, Titli,Mukherji, Ananya,Srivastava, Hemant Kumar,Kancharla, Pavan K.. "Secondary amine salt catalyzed controlled activation of 2-deoxy sugar lactols towards alpha-selective dehydrative glycosylation". supporting information. p. 2870 - 2875. Retrieved 2018/05/03.
• 3、 Bownik, Iwona,?ebej, Peter,Literák, Jaromír,Heger, Dominik,?imek, Zdeněk,Givens, Richard S.,Klán, Petr. "4-Hydroxyphenacyl Ammonium Salts: A Photoremovable Protecting Group for Amines in Aqueous Solutions". . p. 9713 - 9721. Retrieved 2015/10/12.